Cenix BioScience Expands Usage of Definiens Technology in High-Content Screening

Definiens, the number one Enterprise Image Intelligence™ Company and Cenix BioScience GmbH, the leading specialist in advanced high throughput (HT) RNA interference (RNAi)-based research services, announced today that they have expanded their mutual licensing agreement. This strategic decision confirms the heightened commitment of Cenix to the use of the Definiens technology within its organization. Resulting from the findings of an internal review Definiens Cellenger^® was reselected as the best available application to support Cenix in the development and implementation of high content (HC) microscopy assays for HT-RNAi studies in cultured human and rodent cells.

Definiens Cellenger is Definiens advanced application for high content analysis that enables the reliable and fully automated extraction of data from images used in cell-based assays. It allows Cenix to analyze structures of interest even in complex images with high accuracy. The flexible and platform-independent application automates and standardizes the company’s image analysis processes - of particular use with multi-parametric cell-based assays. For this innovative technology, Definiens gained the 2007 Frost & Sullivan Technology Leadership Award in the US high-content screening market, which is based on a detailed analysis of the high content screening market executed by Frost & Sullivan.

With Definiens Cellenger Cenix is able to handle the most challenging demands of image analysis tasks, covering every assay development need. The application will be integrated into the existing HT/HC-RNAi-based research infrastructure at Cenix, enabling the widest possible range of advanced microscopy-based assays in its research service offerings.

Dr. Michael Hannus, Group Leader, Cell-based Discovery & Validation at Cenix BioScience, said “After we tested and reviewed the available high content screening software, it became obvious that there is no other solution out there that can support us in the extremely challenging image analysis tasks we perform for our customers.”

Cenix BioScience provides research services to the life science industry and the academic community, focusing on the combination of HT-RNAi with HC assays in human and rodent cells. In its efforts to further strengthen its capabilities in microscopy-based screening and automated image analysis, Cenix BioScience reviewed a wide range of image analysis solutions offered by academia and industry.

“We are pleased with Cenix‘s decision to intensify the use of our product in its laboratories,” stated Rene Hermes, Vice President Marketing, Definiens. “Its decision is recognition of the unmatched possibilities that our technology offers to customers for developing automated image analysis applications.”