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6545 Q-TOF LC/MS

Agilent TechnologiesAvailable: Worldwide

Raising the standard for mid-range Q-TOF instruments, the Agilent 6545 Accurate-Mass Q-TOF LC/MS system offers higher resolving power and sensitivity that is on the order of five times higher than our earlier workhorse instruments. Incorporating the new fast and powerful SWARM autotune feature, the 6545 enables every user to the get the best results—whether your lab is focused on profiling metabolomics or lipidomics, screenin…

Agilent Technologies

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Average Rating 4.3

|9Scientists have reviewed this product

Ease of Use
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A good and ease to use equipment for high resolution.

 

Average Rating 3.7

Application Area:

Pharmaceutical

The equipment meets the application expectations, mainly in terms of high resolution. We haven't used it for quantitative experiments yet. The software and routine maintenance are really intuitive and easy to follow. The after-sales service leaves something to be desired in Brazil, as few technicians with more experience are available for prompt service. Regarding the cost, it is not one of the most expensive equipment.

Review Date: 15 May 2023 | Agilent Technologies

Great instrument to reassert your findings!

 

Average Rating 4.3

Application Area:

Analyze protein samples

A very effective instrument for determining, as well as confirming contents of protein samples. The instrument is very reliable, in which data is very reproducible. Once the standard applications of the instrument have been established, it is fairly straightforward to use as it is user-friendly. It also provides a wide range of method development, in order to best suit the type of samples and analysis that you are looking for. I highly recommend this instrument.

Review Date: 9 Dec 2021 | Agilent Technologies

Extraordinary results. I won't abandon this instrument.

 

Average Rating 4.0

Application Area:

Laboratory

The after sales support is well explained so you will understand it easily.

Review Date: 15 Jul 2021 | Agilent Technologies

Very useful instrument. Great results in compound discovery and quantitation.

 

Average Rating 4.7

Application Area:

Compound discovery

We use this high-resolution mass spectrometry instrument for compound discovery. We can now perform non-target analysis searching for extractables and leachables (a.k.a. NIAS) in food contact materials. The 6545 mass spectrometer is a powerful tool for research as well as for quantitation purposes due to it having an analytical mode in which you can emulate a triple quad and it can be used to reach ppb level of quantitation. The instrument comes with Mass Hunter software and MSC software which is a very strong tool for compound discovery. Very polyvalent instrument.

Review Date: 7 Apr 2021 | Agilent Technologies

Very useful instrument. Great results in compound discovery and quantitation.

 

Average Rating 4.7

Application Area:

Analyze NIAS in food contact materials

We use this high-resolution mass spectrometry instrument for compound discovery. We can now perform non-target analysis searching for extractables and leachables (a.k.a. NIAS) in food contact materials. The 6545 mass spectrometer is a powerful tool for research as well as for quantitation purposes due to it has an analytical mode in which you can emulate a triple quad and it can be used to reach ppb level of quantitation. The instrument comes with Mass Hunter software and MSC software which is a very strong tool for compound discovery. Very polyvalent instrument.

Review Date: 6 Apr 2021 | Agilent Technologies

Great results, interesting conclusions using the instrument's software (MPP).

 

Average Rating 4.7

Application Area:

Analyze metabolites of different origin, natural products, organic synthesis, pharmaceutical etc.

Great instrument with good mass accuracy, easy to calibrate and run individual samples or batches. Reproducible results, several ways to acquire data depending on the nature of sample. Easy to run with or without internal standard and quality control samples. We have analyzed natural product samples, pharmaceutical, biologics, and synthetic origin. Mass Hunter software for data processing is easy to use for qualitative, quantitative or multivariate analysis. I can recommend this instrument.

Review Date: 22 May 2020 | Agilent Technologies

It is okay

 

Average Rating 3.7

Application Area:

Vet drugs screening

Not easy to use. Drift mass too much. Need more service support

Review Date: 17 Apr 2018 | Agilent Technologies

High resolution it's amazing

 

Average Rating 4.3

Application Area:

Drug discovery

This system provides fast and accurate answer for identification of unknown compounds. It's valuable tool in lab.

Review Date: 16 Apr 2018 | Agilent Technologies

Good results with affordable cost

 

Average Rating 4.3

Application Area:

Analyse organic molecules in organic synthesis samples, Analyse metabolites in plant tissue samples.

This is a good system for HRMS applications. Agilent people are really good at custmer support, I used this system for MS/MS studies. This software (masshunter) provides plenty of options to play with data but it needs some more optimisation.

Review Date: 31 Oct 2017 | Agilent Technologies

Raising the standard for mid-range Q-TOF instruments, the Agilent 6545 Accurate-Mass Q-TOF LC/MS system offers higher resolving power and sensitivity that is on the order of five times higher than our earlier workhorse instruments. Incorporating the new fast and powerful SWARM autotune feature, the 6545 enables every user to the get the best results—whether your lab is focused on profiling metabolomics or lipidomics, screening food and environment samples, or pharmaceuticals. By combining the power of the 6545 with efficient MassHunter data-mining tools and PCDLs, you can generate answers faster and with greater confidence than ever before.

Features:

  • New, fast autotune improves sensitivity up to 5x for small molecule applications
  • Autotune technology also helps preserve fragile compounds for improved detection
  • New Agilent high voltage pulser and power supplies increase mass resolution performance and enhanced mass accuracy to 0.8 ppm
  • New ion optics elements provides greater robustness
  • New ion beam shaping optics provide more consistent results and longer usage time between cleanings
  • Enhanced gain shifted detector increases life time up to 3X

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