Products & ReviewLife Sciences
Alt-R™ CRISPR-Cas9 crRNA XT
Integrated DNA Technologies Inc.Available: Worldwide
Guide RNAs (gRNAs) contain the target-specific sequence for guiding Cas9 protein to a genomic location.
Must be used with tracrRNA to form a functional gRNA duplex. Suitable for challenging experimental conditions (e.g., high nuclease environments or with Cas9 mRNA). Contain additional chemical modifications compared to crRNA to provide a cost-effective option for increased stability.