Bioruptor® Plus
The Bioruptor® uses a unique system to uniformely process multiple samples in sealed tubes of 0.5 ml to 50 ml capacity. An excellent device for shearing chromatin or DNA, cell and tissue disruption and many other applications. Diagenode’s Bioruptor® Plus uses a gentle method of sonication to retain the integrity of DNA and/or biological complexes, including chromatin, protein-protein binding, protein-DNA complexes and othe…
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Highly effective
Protein aggregation and seeding
Easy to use, works well if you want to purify amyloids from tissue samples.
Review Date: 25 Sept 2022 | Diagenode
So far it is good.
Sonication, I POND, ChIP
We just bought the Bioruptor, so far it is good.
Review Date: 30 Apr 2019 | Diagenode
Reproducible results every time
Sonication for ChIP-seq-eq
Very easy to use, no worries about the heating, high throughput.
Review Date: 29 Nov 2016 | Diagenode
Great Instrument and considered a must have in our lab.
Extraction of protein & RNA/DNA from small volume tissue samples for downstream analysis.
Easy setup and straightforward to operate. Great technology in that it keeps your samples at low temps during sonication/homogenization of tissues and is high efficiency. Process is contained within each tube so there's no risk of cross-contamination.
Review Date: 28 Jun 2016 | Diagenode
A must have when performing ChIP
Tissue Homogenization for ChIP
Excellent instrument for DNA shearing from tissue. Had attempted using a sonicator which destroyed my DNA and protein. The Bioruptor consistently sheared my DNA to an appropriate size and did not disrupt the protein.
Review Date: 18 Dec 2015 | Diagenode
The Bioruptor® uses a unique system to uniformely process multiple samples in sealed tubes of 0.5 ml to 50 ml capacity. An excellent device for shearing chromatin or DNA, cell and tissue disruption and many other applications.
Diagenode’s Bioruptor® Plus uses a gentle method of sonication to retain the integrity of DNA and/or biological complexes, including chromatin, protein-protein binding, protein-DNA complexes and other biochemical and biological assay systems. The Bioruptor® Sonication System uses a sonication bath to generate indirect sonication waves, which emanate from an ultrasound element below the water tank. Because the system is gentler than other sonicators, the Bioruptor® produces better and more consistent results than with harsher sonication methods. Up to 12 closed tubes can be sonicated in parallel and the continuous rotation of tubes allows even distribution of the energy for efficient sonication. The Bioruptor® enables automation of sonication, guaranteeing higher reproducibility of results.
Features:
- Digital timer
- Metal soundproof box
- Overheat shutdown protection (this feature is not available in the US)
- Machine lifetime control
Applications:
- Chromatin Shearing
- DNA Shearing
- Cell & Tissue disruption
