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Bone Cell Lines

KerafastEKC001-EKC004Available: Worldwide

IDG-SW3 bone cell line and murine osteocyte-like cell lines MLO-Y4 & MLO-A5

Kerafast

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We offer the following cell lines for studying bone growth and development:

  • IDG-SW3 Bone Cell Line: replicates osteoblast to late osteocyte differentiation in vitro and increases bone formation in vivo
  • Murine Osteocyte-like Cell Line MLO-Y4: useful for studying the effects of fluid flow and substrate stretching on the activation of osteocyte-specific signaling pathways; offers high expression of osteocalcin, connexin 43 and the antigen E11
  • Murine Osteocyte-like Cell Line MLO-A5: model for osteoblast-to-osteocyte differentiation, the mineralization process and the effects of mechanical loading on biomineralization; expresses various markers of the late osteoblast

All come from the laboratory of Dr. Lynda F. Bonewald at the University of Missouri - Kansas City. 

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