Products & ReviewLife Sciences
Dibutyryl-cAMP
cAMP pathway activator; Activates cAMP-dependent protein kinases
Dibutyryl-cAMP
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Dibutyryl-cAMP is a cell-permeable cyclic AMP (cAMP) analog that activates cAMP-dependent protein kinases (Schwede et al.). This product is supplied as the sodium salt of the molecule.
DIFFERENTIATION
- Suppresses experimental autoimmune encephalomyelitis development by reducing demyelination and mobilizing neural stem cells in the subventricular zone towards the demyelinated plaques (Khezri et al.).
- Induces intrinsic axon growth in peripheral and central nervous systems, and morphological differentiation of astrocytes (Knott et al.; Imamura & Ozawa).
- Stimulates neurite outgrowth in PC12 cells (Maruoka et al.).
