FabRICATOR® Enzyme
The FabRICATOR Enzyme is supplied as a lyophilized powder with no preservatives added, and is available in 2000 and 5000 unit vials for digestion of up to 2 - 5 mg IgG.
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Highly specific and efficient enzyme
Enzyme for monoclonal antibody
The IdeS/Fabricator enzyme provides a very specific and highly efficient cleavage to create subunits from IgG1 mAbs, which are very useful for LC-MS analyses.
Review Date: 26 Mar 2019 | Genovis
The FabRICATOR Enzyme is supplied as a lyophilized powder with no preservatives added, and is available in 2000 and 5000 unit vials for digestion of up to 2 - 5 mg IgG.
FabRICATOR (IdeS) is a cysteine protease that digests antibodies at a specific site below the hinge, generating a homogenous pool of F(ab')2 and Fc/2 fragments after 30 min incubation.
