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FLIPR Penta® High-Throughput Cellular Screening System

Molecular Devices®FLIPRAvailable: Worldwide

High-throughput kinetic screening for lead compound identification and compound safety assessment

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Building on the success of the industry-leading FLIPR platform for monitoring of GPCRs and ion channels, the FLIPR High-Throughput Cellular Screening System offers a new high-speed camera option and the new Peak Pro 2 software module, allowing you to measure and analyze patterns of calcium oscillations of human iPSC-derived cardiomyocytes and neurons. Images can be taken at up to 100 times per second and patterns quickly analyzed using more than 30 various measurements.

Available with a range of pipettors, optics, and automation options, the system can be configured based on library size, detection mode, screening format, assay, and target, making the transition from assay development to lead optimization a seamless process.

Key benefits:

  • Assay adaptability with configurable optics
  • Throughput flexibility with user-exchangeable 96-, 384-, and 1536-well pipettors
  • Multi-user flexibility with intuitive software
  • Future ready with FLIPR Cycler automation upgradeability

The FLIPR Penta System supports a wide range of assays, such as GPCR assays using FLIPR Calcium Assay Kits and Membrane Potential assays using the FLIPR Membrane Potential Assay Kit, FLIPR Potassium Assay Kit, and FLIPR Calcium Assay Kit. Cardiomyocytes can also be used to evaluate compound effects earlier in the drug discovery process with the EarlyTox Cardiotoxicity Kit.

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