Human Nav1.1 Sodium Channel Division-Arrested Cells
The human SCN1A gene encodes the pore-forming subunit of voltage-gated type-1 Na+ channels. Neuronal Nav1.1 channels are therapeutic targets in seizure, pain, and stroke. Synonyms: brain type-1 sodium channel Host cell: CHO-K1 Gene name: SCN1A Mycoplasma status: Negative (MycoAlert Kit) Packaging: Three vials of Cyropreserved irradiated cells, 2 x 106 cells/vial (6x106 cells total) Growth media: Ham’s F12; 10% FBS Growth char…
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The human SCN1A gene encodes the pore-forming subunit of voltage-gated type-1 Na+ channels. Neuronal Nav1.1 channels are therapeutic targets in seizure, pain, and stroke.
Synonyms: brain type-1 sodium channel
Host cell: CHO-K1
Gene name: SCN1A
Mycoplasma status: Negative (MycoAlert Kit)
Packaging: Three vials of Cyropreserved irradiated cells, 2 x 106 cells/vial (6x106 cells
total)
Growth media: Ham’s F12; 10% FBS
Growth characteristics: cells remain viable 1–2 days post-thaw
Storage recommendation: frozen under liquid nitrogen
Functional expression: median Na+ current amplitude = 0.80 nA
Recommended assays: manual or automated patch clamp