Invitrogen™ CellEvent™ Caspase 3/7 Green Ready Flow™ Reagent
CellEvent Caspase-3/7 Green Ready Flow Reagent enables the flow cytometric detection of activated caspase-3 and caspase-7 in apoptotic cells. The product includes 2 reagents: the novel fluorogenic substrate CellEvent Caspase-3/7 Green Detection Reagent and SYTOX™ AADvanced™ Dead Cell Stain.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteExceptionally bright green fluorescen…
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CellEvent Caspase-3/7 Green Ready Flow Reagent enables the flow cytometric detection of activated caspase-3 and caspase-7 in apoptotic cells. The product includes 2 reagents: the novel fluorogenic substrate CellEvent Caspase-3/7 Green Detection Reagent and SYTOX™ AADvanced™ Dead Cell Stain.
Features
- Stable at room temperature
- Convenient, ready-to-use format—no need to dilute, weigh, or pipette
- Exceptionally bright green fluorescence upon binding to nucleic acids
- Rapid staining of apoptotic cells without wash steps
CellEvent Caspase-3/7 Green Ready Flow Reagent consists of a four-amino acid peptide (DEVD) carrying the cleavage recognition site of caspase 3/7 conjugated to a nucleic acid-binding dye. During apoptosis, when caspase-3 and caspase-7 proteins are activated, they cleave the DEVD peptide while the nucleic acid binding dye labels the apoptotic cells with a bright, fluorescent signal having absorption/emission maxima of ~502/530 nm. When used together with the SYTOX AADvanced Dead Cell Stain, apoptotic cells can be easily discriminated from live and necrotic cells.
