isoCell – Single Cell Cloning Automation
The isoCell helps automate your single-cell cloning experiments without complex protocols. This instrument miniturises cell culture volumes and almost eliminates all manual pipetting steps. Utilising our GRID technology, users can confidently confirm monoclonality on day 0. With a compact footprint and easy-to-use interface, the isoCell is one of the smallest but most powerful instruments for single-cell cloning available.
isoCell instrument
Single-cell chamber after plating day 0
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isoCell - much more than a single-cell dispenser
The isoCell instrument automates all liquid-handling and minimises reagent wastage. It dispenses cells, exchanges culture media and harvests clonal cultures for downstream applications, all without the need for tedious manual pipetting. With the isoCell, cells are handled using low pressure and low shear forces. Together with optional heating, it delivers exceptional cell viability. Traditional single-cell cloning methods utilise volumes of cell culture media that quickly add up and rapidly increase the cost of your experiments; alternatively, the isoCell uses nanolitre culture volumes, drastically reducing costs and wastage.
All of this functionality sits within the most compact system on the market — the isoCell fits neatly into any biosafety cabinet without obstructing any other ongoing cell culture work. Now you can also unlock consistent results in every experiment.
Feature highlights:
- Automate all tedious pipetting steps
- Maintains exceptional cell viability
- Market-leading cloning efficiencies
- Compatible with a wide range of reagents
- Consistent and reproducible performance
- Low pressure of <0.5 psi makes cell handling incredibly gentle
- Minimises cell culture media usage with only 600 nL per chamber
- Up to 25x more clones per mL of culture medium compared to other methods
- Easily navigate the entire cloning workflow with an intuitive touchscreen
- Highest assurance of clonality, as single cells can easily be visualised immediately after plating on day 0
Suitable for single-cell cloning of:
- hiPSCs
- ESCs
- HEK293
- CHO
- RPE1
- And many more – get in touch to discuss your requirements
