myMATRIX MSC
Serum-free and chemically defined mesenchymal stromal cell culture
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Useful tool to increase MSCs yield. A way to save money. Good results.
Adult stem/stromal cells cultivation
This is a 6 well plate coated with a matrix allowing mesenchymal stem cells to grow without serum. A useful tool for clinical use. A good tool to evaluating the best matrix for specific MSCs from different tissues and donors.
Review Date: 24 Dec 2020 | denovoMATRIX GmbH
denovoMATRIX provides a chemically defined cell adhesion-promoting microenvironment offered as pre-coated cultureware, specially formulated for expansion of human mesenchymal stromal cells (hMSC) in serum-free and xeno-free media.
- Chemically defined coating
- Serum-free and xeno-free hMSC culture
- Ready-to-use
- Lot-to-lot consistency
denovoMATRIX aims to streamline your cell culture process. Our products are manufactured and shipped as ready-to-use cultureware. No elaborate coating, washing steps or dedicated solutions necessary, which also reduces the risk of contamination. You can store them at room temperature for up to one year before usage, and don’t have to worry about space in your fridge or cold storage room. Use myMATRIX MSC in combination with many dissociation reagents, media and supplements.
- Ready-to-use: coating preparation time eliminated
- Reduce contamination risk by 90 %
- Free up fridge space: myMATRIX MSC is stored at room temperature
- Compatible with various reagents and media
denovoMATRIX technology incorporates biologically relevant polymers to recreate essential elements of the cell microenvironment. One of them includes the synthetic peptide sequence ‘RGD’ that facilitates cell adhesion by stimulating integrin receptors of the cells. In addition, myMATRIX MSC contains a sulfated polysaccharide, which mimics the function of glycosaminoglycans (GAG). In vivo, GAGs are instrumental in stabilizing and storing soluble factors. As an example, the Fibroblast Growth Factor (FGF-2) is stabilized over 24 hours on myMATRIX MSC. Thus, the myMATRIX MSC replicates the in vivo environment more accurately than existing technologies. myMATRIX MSC is tailored to create optimal expansion conditions for human mesenchymal stromal cells (hMSC), also termed mesenchymal stem cells.
- Storage at room temperature
- Optimized composition for serum-free culture of hMSC
- Adhesion peptide sequence enables integrin-specific cell interaction
- Glycosaminoglycan-mimetic facilitates paracrine signaling
