Products & ReviewLife Sciences
OAC1
Inducer of OCT4 expression
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
OAC1 is an OCT-4-activating compound that activates expression through the OCT-4 gene promoter (Li et al.). Oct-4 (POU5F1) is a transcription factor that is critically involved in the self-renewal of pluripotent stem cells, and its expression is commonly used as a marker for pluripotency.
REPROGRAMMING
- Enhances the reprogramming efficiency of mouse embryonic fibroblasts transfected with OCT4, SOX2, KLF4, and c-MYC (Li et al.).
MAINTENANCE AND SELF-RENEWAL
- Mediates ex vivo expansion of cord blood CD34+ hematopoietic stem and progenitor cells (Huang et al.).