Octet® R8 BLI System
Superior quantitation and kinetics performance with increased assay flexibility and cost efficiency.
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BLI makes kinetic characterization and quantitation easy!
Kinetics & quantitation
Octet R8 is a great equipment for any lab which would like to test their samples for binding, do kinetic characterization and sample quantitation. It is quite fast and informative (compared to techniques such as ELISA), but it is costlier.
Review Date: 13 May 2024 | Sartorius Group
Would buy that instrument again.
IgG Quantitation in Cell Line Development
Easy to use instrument, good results. Easy to explain to new users. Great support.
Review Date: 14 Jul 2022 | Sartorius Group
Superb instrument, ideal for high throughput work!
Protein-ligand and Protein-protein interaction, fragment based drug development
The equipment is very easy to operate and great user interface. Moreover, we have achieved great results in our experiments. In fact, we need a very less quantity of protein/ligand to quantitate. It is extremely fast and can perform high throughput experiments easily. Great for screening purposes.
Review Date: 2 Apr 2022 | Sartorius Group
First choice for interaction studies.
Drug discovery
Octet is very easy to use system for fast screening of protein - small molecule interaction studies. Easy to maintain and definitely value for the money because of time saved in measurements time.
Review Date: 20 Jan 2022 | Sartorius Group
Great results, can’t live without this instrument!
Drug discovery
State of the art technology
Review Date: 19 Jan 2022 | Sartorius Group
Great value
High throughput screen
This machine is user-friendly and easy to use, which can be used for HTS.
Review Date: 19 Jan 2022 | Sartorius Group
Great results
Analysis
Great results
Review Date: 19 Jan 2022 | Sartorius Group
Using BLI technology - Octet R series has no match
Drug discovery
Octet R series is fast, easy to use & software is very friendly. Results can be obtained in 3 - 4 hrs run time, even with low volume samples. I strongly recommend as it is very economical , compared to other players in market. Efficient sales & service team to serve customers. Prompt service by team Sartorius.
Review Date: 11 Jan 2022 | Sartorius Group
Powerhouse biomolecular equipment.
Protein ligand binding and antibody kinetics
A powerful addition to our lab. The striking feature that comes up time and again is that the sample is preserved so the ability to control experiments and analyse samples by other techniques is a huge advantage over injection-based flow systems. I can run multiple antibodies through the very same sample and be certain that the result is real and not just ruled out as an anomaly or error.
Review Date: 7 Dec 2021 | Sartorius Group
A must have instrument for drug/antibody discovery and vaccine research labs.
Antibody discovery, discovery and clinical
Octet is one of the best system for determination of binding constants, antibody discovery and vaccine research. It is versatile with various chemistries for ligand immobilization. High throughput, robust, easy to use and excellent technical support.
Review Date: 3 Mar 2021 | Sartorius Group
The 8-channel system - Octet® R8 - offers an advanced fluidics-free approach to protein characterization. The independent biosensors allow analysis of single or up to eight channels, enabling flexibility in sample throughput based on need. The Octet system performs quantitation of 96 samples in 32 minutes and kinetic screening of 64 samples in 1.5 hours.
The system utilizes Bio-Layer Interferometry (BLI) technology. The real-time technique enables direct detection of specific proteins and other biomolecules — even in complex mixtures like cell culture supernatants and lysates and low concentration environments.
Furthermore, the label-free technology gathers physiologically relevant data quickly, proving to be a cost-effective method.
Key Benefits:
- Large dynamic range for comfortable titer determination Versatile kinetic analysis from small molecules (150 Da) to cells
- Temperature Control (15–40°C) Evaporation protection for long off-rate measurements
- Full post-analysis sample recovery Low maintenance and operational costs
- Ready for GxP regulated environments
Popular industrial applications include expression screening, on- and off-rate screening, epitope binning, cell line development and bioprocess optimization.
The Octet® R8 system is widely used in analytical core labs for protein structure/function studies and small molecule screening campaigns. The system has been developed to operate reliably in a regulated environment. Sartorius offers 21 CFR Part 11 software and a full line of GxP products and services as part of the Octet® R8 GxP Package.
