Products & ReviewClinical Diagnostics
Parsortix™ System
ANGLE plcAvailable: North America,Western Europe,
Capture and harvest of circulating tumour cells from whole blood.
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The Parsortix system from ANGLE uses a patented micro-fluidic technology in the form of a disposable cassette to capture and then harvest circulating tumour cells (CTCs) from whole blood. The cassette captures CTCs based on their less deformable nature and larger size as compared to other blood components.
Benefits:
- Capture and harvest of CTCs for a wide range of cancers including prostate, breast, lung, colo-rectal, renal and ovarian.
- Cell capture does not require the use of antibodies hence allowing for capture of cells with weak cell marker expression (such as ovarian, liver and melanoma) as well as mesenchymal cells and clusters of cells.
- Ability to process up to 20ml of whole blood.
- Very simple operation with minimal user intervention required and no pre-processing of blood necessary.
- Customisable in-cassette staining protocols using up to six separate reagents.
- Harvest of intact CTCs in <100µl, ready for downstream analysis.
Applications:
- Enumeration of CTCs in patient blood samples.
- Harvesting of CTCs from patient blood ready for genetic or protein analysis such as: FISH, qPCR, Next generation sequencing, Immuno-histochemistry.
The Parsortix system is CE marked for use as an in vitro diagnostic device in the EU.
The system is available for research purposes in the US, but does not have FDA approval for clinical purposes.
