Enrichment and Isolation of Uncontaminated Breast Cancer Cells from Human Blood Samples using ANGLE’s Parsortix System

Cancer cells in peripheral blood, known as circulating tumor cells (CTCs), play an important role in tumor dissemination. The molecular characterization of CTCs is important because it may provide insights into the molecular biology of metastasis, the association of their molecular profiles with treatment outcomes, and reveal the presence of potential therapeutic targets. This scientific poster presents a method used to isolate CTCs which combines the Parsortix System, microfluidic cell separation device, as an enrichment method followed by the DEPArray selection system. The ParsortixTM system is versatile in its ability to separate, capture and harvest CTCs in an enriched form compatible with the needs of downstream processes such as DEPArray.