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Phenylmethanesulfonyl fluoride

Merck KGaA, Darmstadt, GermanyP7626Available: Worldwide

≥98.5% (GC)

Merck KGaA, Darmstadt, Germany

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Average Rating 4.5

|2Scientists have reviewed this product

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Recommend for organic synthesis.

 

Average Rating 4.7

Application Area:

Organic synthesis

Highly preferred.

Review Date: 19 Nov 2021 | Merck KGaA, Darmstadt, Germany

Pure products give good results.

 

Average Rating 4.3

Application Area:

Synthesis

Highly pure and great for synthesis.

Review Date: 16 Jul 2021 | Merck KGaA, Darmstadt, Germany

Inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase. Not as effective or as toxic as DFP. Effective concentration 0.1-1 mM. Half-life = 1 hr. at pH 7.5.

Phenylmethanesulfonyl fluoride has been used in following applications:

  • cell fractionation.
  • used as a supplement in nuclear protein extraction.
  • inhibitor of cholesterol esterase (CE) and pseudocholinesterase (PCE).
  • used for the collection of blood prior to centrifugation to quantify plasma ANP levels.

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