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ProteomeLab XL-A/XL-I Analytical Ultracentrifuge (AUC)

Beckman Coulter Life Sciences392764Available: Worldwide

Native-condition characterization for accurate results every time

Beckman Coulter Life Sciences

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Average Rating 3.3

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Average Rating 3.3

Application Area:

Particle sizing, molar mass determination

Very useful equipment for separation and molecular weight determination that does not require a separating matrix as is found in HPLC and SEC methods. However it is expensive to maintain and does not come with extensive data analysis software.

Review Date: 16 May 2012 | Beckman Coulter Life Sciences

Beckman Coulter pioneered the field of analytical ultracentrifugation and continues to design and produce powerful, reliable, and durable instrumentation to enable academic and industrial research around the world. By measuring proteins as interacting elements, ProteomeLab XL-A and XL-I systems accelerate the development of diagnostic markers and therapeutic targets for efficient and reliable protein characterization in solution. Each ProteomeLab system is designed to put actionable information in your hands quickly and easily. Native-condition characterization for better lead optimization, better drug candidate evaluation, better method validation....better science. The ProteomeLab XL-A/XL-I in-solution characterization of proteins, oligomers, aggregates, particles, colloids, and small structures delivers accurate results you can rely on time and again. In-solution characterization allows for testing in native conditions, meaning you determine the sample testing environment that best suits your needs. The unique column-free separating technique of the ProteomeLab XL-A/XL-I measures the relative change in the distribution of molecular weights, providing an efficient way to measure heterogeneity, stoichiometry and self-associating systems. And, because the measurements are based on the first principles of thermodynamics and hydrodynamics, no standards or calibrations are required. As a result, you spend less time on setup and more time on discovery.

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