Qube High Throughput Screening System
The Qube is Sophion's next generation high-throughput system for ion channel screening, intended for use in laboratories with a need for thousands of data points per day. The Qube finally bridges the gap between high-throughput and high quality in ion channel assays.The Qube can be used for primary and secondary screening of any ion channel of interest. Sophion's vast experience with planar patch clamp from the QPatch products…
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Data quality has improved.
EPhys - Safety work
The equipment is very easy to use and software is user friendly. Provides high quality data.
Review Date: 27 Jun 2018 | Sophion Bioscience
The Qube is Sophion's next generation high-throughput system for ion channel screening, intended for use in laboratories with a need for thousands of data points per day. The Qube finally bridges the gap between high-throughput and high quality in ion channel assays.
The Qube can be used for primary and secondary screening of any ion channel of interest. Sophion's vast experience with planar patch clamp from the QPatch products has been utilized to create gigaseal recording substrates and flow channels for liquid exchange in the Qube measurement plates. With 384 parallel measurement sites and as little as 10-15 minutes per plate run, the Qube enables testing more than 1500 compounds in a single hour. With full automation features - a plate stacker and cell preparation unit - for unattended operation, the system provides walk-away time, which the scientist can use for other important tasks. The Qube is easy to operate with user-friendly software for experiment setup, automated data analysis and data export.
Features:
- Throughput of over 10,000 compounds tested per day
- 384 simultaneous recordings in whole-cell patch clamp configuration
- 384 parallel amplifiers for high-quality patch clamp recordings
- Gigaseal resistances in recordings
- Excellent voltage clamp
- Excellent liquid exchange for multiple compound additions
- Cell membrane parameter compensations
- 384 pipettes with exchangeable tips
- Plate recording time approx. 15 minutes, for simplest assay
- Single-hole recordings (single-cell patch clamp)
- Multi-hole recordings (multi-cell patch clamp with 10 cells per well)
- Full automation for maximal walk-away time
- Cell preparation station
- Plate stacker unit
- User friendly software for data analysis and experiment setup
