Raptor™ Biphenyl LC Column
With Raptor™ LC columns, Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. SPP core-shell columns commonly employ traditional phe…
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Superior alternative to popular C18 phase columns
Ideal for food, bodily fluids, and other difficult matrices
Raptor SSP columns offer great separation of a broad range of compounds that is not possible with C18 phase columns. I decided to make the change to this column to heighten selectivity of difficult analytes.
Review Date: 21 Nov 2022 | Restek Corp.
Excellent Columns
LC-MS of biological fluids
Excellent product - the entire range of RAPTOR columns has outstanding connections (fingertight). Very good quality and robustness. Price is above par for the industry, among LC column manufacturers, but worth it.
Review Date: 28 Sept 2022 | Restek Corp.
Best separation for isomers. Fantastic.
Steroid analysis
It's easy to set up my method and the after sales support is helpful. It's worth the money in every aspect.
Review Date: 9 Feb 2021 | Restek Corp.
Great performer.
Analytical chemistry
Raptor Biphenyl LC columns are very versatile and suitable for analysis of a wide range of drugs including very polar molecules such as morphine and codeine glucuronides.
Review Date: 24 Dec 2020 | Restek Corp.
Excellent performance, robust, reproducible and reliable. A++.
Bioanalytical testing applications like drug and metabolite analyses
This column recommended and shared by our Restek representative became extremely useful in analyzing and resolving analytes/derivatives that were hard to resolve or elute early on other C18 and phenyl columns we tried.
Review Date: 24 Dec 2020 | Restek Corp.
Great column life!
UHPLC/MS/MS Column
Best column life we have found! Restek columns have saved us so much money by not needing to order a new one every three months like other columns we've used. Very stable and easy to use, absolutely great all around!
Review Date: 3 Mar 2020 | Restek Corp.
Great column for urine drug testing.
Clinical lab
The Raptor HPLC column for urine drug testing give good resolution and consistent RT from column to column. We get approximately 5000 injections per column.
Review Date: 9 Dec 2019 | Restek Corp.
Happy with results & support.
Serum analysis for steroids
This biphenyl column has been great for my steroids application, it’s helped me achieve separation for isobaric steroids improving specificity.
Review Date: 9 Dec 2019 | Restek Corp.
Very good separation, fit perfectly to our application.
Oral fluids testing
The application notes are very concise, though not a lot of details are shared.
Review Date: 9 Dec 2019 | Restek Corp.
Great results, Can't complain.
Drug analysis
We achieve high quality seperation and reproducibilty for drug analysis with Raptor Biphenyl 2.7 uM 100 x 2.1 uM columns. It's easy to install and change.
Review Date: 9 Dec 2019 | Restek Corp.
With Raptor™ LC columns, Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.
SPP core-shell columns commonly employ traditional phenyl-hexyl stationary phases, but the innovative Biphenyl ligand, developed by Restek’s chemists, is the next generation of phenyl column chemistry. It provides greater aromatic selectivity than commercially available phenyl-hexyl columns[1] and a greater degree of dispersion than conventional phenyls. As a result, the Raptor™ Biphenyl allows you to more easily separate bioanalytical compounds like aromatics, which elute early or are hard to separate on C18 or other phenyl chemistries.
One of the greatest advantages of an SPP column is the ability to achieve fast, efficient separations by operating at higher linear velocities than are possible with a convbentiaonal fully porous particle column. However this can also result in higher back pressures. Raptor™ columns were designed to handle the increased pressures needed to achieve Selectively Accelerated, and handle it far better than other SPP columns on the market.
Raptor™ Biphenyl LC Column Features & Benefits:
- Higher efficiency for drastically faster analysis times.
- Better selectivity for substantially improved resolution.
- Increased sample throughput with existing HPLC instrumentation.
- Ideal for bioanalytical testing applications like drug and metabolite analyses.
- Heightened selectivity and retention for compounds that are hard to resolve or elute early on C18 and other phenyl chemistries.
- Limits ionization suppression and allows simple, MS-friendly mobile phases.
- Restek's most popular LC stationary phase applied to Raptor™ SPP core-shell silica.
Column Details:
- Stationary Phase Category: Phenyl (L11)
- Ligand Type: Biphenyl
- Particle: 2.7um SPP
- Pore Size: 90 Å
- Surface Area: 150 m2/g
- Length: 30 - 150 mm
- ID: 2.1, 3.0, 4.6 mm
