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Thermo Scientific™ Bond-Breaker™ TCEP Solution, Neutral pH

Bond-Breaker TCEP Solution is a stable thiol-free, phosphine-based TCEP compound useful as a replacement for Beta-mercaptoethanol or DDT in SDS-PAGE sample buffers.

Thermo Fisher Scientific

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Average Rating 4.7

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Average Rating 4.7

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Review Date: 31 Jul 2022 | Thermo Fisher Scientific

Bond-Breaker TCEP Solution is a potent, odorless, thiol-free reducing agent with broad application to protein and other research involving reduction of disulfide bonds. This product is an effective and convenient replacement for B-mercaptoethanol or DTT in SDS-PAGE sample buffers. The neutral pH of this reagent provides sharp bands and avoids exposing proteins to the strong acid of TCEP·HCl, which can result in hydrolysis and carbohydrate modification.

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