TRS100 Quantitative Pharmaceutical Analysis System
The TRS100 enables fast, easy-to-use whole tablet or capsule content uniformity and polymorph screening for pharmaceutical finished-product testing and formulation development. Easier to implement than other spectroscopic methods, Agilent's transmission Raman spectroscopy (TRS) technology allows simple method development and deployment for quantitative analysis in quality control applications.
Analyze small molecules (DS and DP)
Agilent TRS 100 Raman spectrophotometer is robust and precise technology to provide accurate results. It has great value for money.
Review Date: 14 Apr 2022 | Agilent Technologies
Content uniformity (solids)
The TRS100 is a powerful technology, which provides huge capabilities with regard to quality control of pharmaceutical products (e.g. assay/content uniformity of solids). The included chemometric software is a professional tool with endless possibilities. The effort of knowledge and resources during method development should not be underestimated. But once it is done, the TRS100 represents a great alternative for classic HPLC analysis.
Review Date: 27 Sept 2021 | Agilent Technologies
Content uniformity testing
Exceptional value for money since it can substitute many HPLC systems and shorten analysis time dramaticaly. Of course there is a great deal of work building up the library and validating new methods.
Review Date: 9 Feb 2021 | Agilent Technologies
Pharmaceuticals
Very good value for money. Has huge capabilities within its application.
Review Date: 20 Jan 2020 | Agilent Technologies
The TRS100 enables fast, easy-to-use whole tablet or capsule content uniformity and polymorph screening for pharmaceutical finished-product testing and formulation development. Easier to implement than other spectroscopic methods, Agilent's transmission Raman spectroscopy (TRS) technology allows simple method development and deployment for quantitative analysis in quality control applications.
A TRS100 system can reduce content uniformity, assay, and ID tests to minutes per batch, saving significant cost and speeding up your quality control workflow. Sample preparation and consumables are not needed, meaning skilled analytical resources are not required. Content uniformity testing methods using transmission Raman have been approved by regulators using ICH and regulatory authority-acceptable protocols.
Features:
- Assay hundreds of tablets or capsules in minutes
- Works with intact capsules and coated tablets of most thicknesses
- No sample preparation, wet chemistry, or skilled testing resources needed
- Quantifies APIs and excipients in a single measurement
- Limit of quantification as low as 0.1% w/w
- Quantifies polymorphs in intact tablets
- Lean calibration models—easy to build and maintain
- Methods approved by regulators
- A range of sample trays and accessories for tablets, capsules, liquids, and powders are available
- Built-in technical controls ensure the security of your data, control access, and facilitate compliance as defined by US FDA 21 CFR Part 11 and EU Annex 11 regulations