Wieslab® Complement MBL Pathway (RUO & IVD*)
The Wieslab® Complement System MBL Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.
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The Wieslab® Complement System MBL pathway kit is an enzyme immunoassay for the qualitative determination of MBL complement pathway and determination of complement deficiencies in human serum. Non-human primate and swine samples can also be assayed with Wieslab Complement System MBL Pathway.
The assay combines the specific activation of each pathway with the use of labeled antibodies specific for a neoepitope of the terminal complement complex, C5b-9, produced as a result of complement activation. The amount of C5b-9 generated is proportional to the functional activity of complement pathways.
The Wieslab Complement assays have been published as a useful tool in evaluation of complement therapeutics, in clinic, clinical trials and in drug development.
