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Thermo Scientific Exactive Plus Orbitrap LC-MS

The Exactive Plus Orbitrap LC-MS is a benchtop full scan mass spectrometer designed for compound identification and high-throughput, high-performance screening. The Exactive Plus delivers high resolution accurate mass (HRAM) data and fast, reproducible results for qualitative and quantitative analysis. The availability of HRAM and full scan capability gives you all the data, all the time. It allows retrospective data analysis…

Thermo Fisher Scientific

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Average Rating 4.4

|20Scientists have reviewed this product

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One of the best instrument for unknown analysis for metabolomics and proteomics

 

Average Rating 4.3

Application Area:

Metabolomics

High quality LCMS, easy to use and can be apply for unknown identification and also quantification

Review Date: 27 Mar 2023 | Thermo Fisher Scientific

Great results

 

Average Rating 3.7

Application Area:

Metabolomics

Easy to use

Review Date: 22 Oct 2022 | Thermo Fisher Scientific

Quality instrument for high quality data

 

Average Rating 5.0

Application Area:

Analyze exosome protein profile

Gain quality results without too many glitches, less chance to get clotted, consistent results, and quick service wait time

Review Date: 28 Sept 2022 | Thermo Fisher Scientific

Lot of applications and easy to use software

 

Average Rating 4.3

Application Area:

Dereplication of plant metabolites

Xcalibur software is very easy to use. A lot of resources for learning how to use it is free and a lot of applications from a lot of labs have been developed. Raw data ready to use with free softwares for their analysis

Review Date: 28 Sept 2022 | Thermo Fisher Scientific

Great results

 

Average Rating 4.0

Application Area:

Drugs

Excellent

Review Date: 17 Jul 2022 | Thermo Fisher Scientific

I like it

 

Average Rating 4.7

Application Area:

Natural products discovery

I like working on LC-HRMS from Thermo Fischer Scientific

Review Date: 21 Jan 2022 | Thermo Fisher Scientific

The best ultra-high-resolution table top mass spectrometer!

 

Average Rating 5.0

Application Area:

metabolomics

In my opinion, this is the only best ultra-high-resolution table top mass spectrometer. Further, the software provided by Thermo makes the instrument easy to operate.

Review Date: 22 Dec 2021 | Thermo Fisher Scientific

Great product.

 

Average Rating 5.0

Application Area:

Forensic toxicology

Great product, Accurate.

Review Date: 25 Jul 2021 | Thermo Fisher Scientific

Great technology.

 

Average Rating 4.7

Application Area:

Drug Analysisa

Great technology, good reproducible results.

Review Date: 24 Jul 2021 | Thermo Fisher Scientific

Best mass spec on the market.

 

Average Rating 5.0

Application Area:

Metabolomics and lipidomics

Most reliable mass spectrometry instrument. The mass accuracy provided is a must when used for metabolomics and lipidomics. Customer service is outstanding.

Review Date: 15 Jul 2021 | Thermo Fisher Scientific

The Exactive Plus Orbitrap LC-MS is a benchtop full scan mass spectrometer designed for compound identification and high-throughput, high-performance screening.

The Exactive Plus delivers high resolution accurate mass (HRAM) data and fast, reproducible results for qualitative and quantitative analysis.

The availability of HRAM and full scan capability gives you all the data, all the time. It allows retrospective data analysis and eliminates MS method development leading to improved and simplified analytical throughput.

Exactive Plus is easy-to-use, cost effective to operate and coupled with workflow-driven software, makes an ideal instrument for new users in routine analytical laboratories.


Selected benefits of the Exactive Plus are specified below:

  • High Resolving Power
  • (up to 140,000) - Eliminates isobaric interferences to increase confidence for analysis or complex samples
  • Mass accuracy - Better than 1ppm in full scan and AIF scan using fully automated AGC and mass calibration procedures offers confident identification
  • U-HPLC Scan Speed - The 12Hz scanning frequency of Exactive Plus is fully compatible with U-HPLC and ensures exact mass measurement for fast chromatography applications
  • Fast Polarity Switching - A full cycle of 1 positive and 1 negative scan is performed within 1 second at a resolution setting of 35,000 without sacrificing mass accuracy
  • All-Ion-Fragmentation (AIF) - With multiple dissociation techniques; in source collisional induced dissociation (CID) and high energy collisional dissociation (HCD), provides MS and MS/MS data
  • Full MS scan, AIF scan, data dependent AIF, alternating Full MS and AIF scan
  • Intuitive software interface

The Exactive Plus Orbitrap LC-MS is ideal for the following applications:

  • Environmental and Food Safety
  • Clinical Research
  • Forensic Toxicology
  • Drug discovery, metabolism and pharmacokinetics (DMPK)
  • Metabolomics
  • Pharmaceutical
  • BioPharma – Intact Protein analysis

Laboratories analyzing food, pharmaceuticals, neutraceuticals, and other complex samples can now purchase Exactive Plus LC-MS system equipped from the factory with IonSense ID-CUBE™ ion sources. This configuration is designed to minimize the need for sample preparation to simplify and speed analyses.

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