Frozen Instant Cells from CCS Cell Culture Service - The Right Amount of Cells, Right in TimeFor secondary screenings where often a limited number of compounds have to be tested, CCS proprietary PRINCESS Instant Assay provides an additional advantage. In Princess Instant Assays cells are frozen directly in assay plates and can be stored at -80°C. According to the need of the project, only the amount of assay plates which is ac…
Ion Channel Cell Lines - Validated in Performance, Accuracy and Quality In cooperation with Cytocentrics AG CCS has developed a set of recombinant cell lines stably expressing ion channels of high pharmacological relevance. The cell lines have been generated by stable transfection of HEK293 or CHO-K1 cells and subsequent clonal selection. They have been characterized in manual and automatic patch clamp assays regarding their…
GPCR Cell Lines - Validated Cell Lines for High-Throughput-Screening In cooperation with Cisbio Bioassays CCS has developed a set of recombinant cell lines stably expressing G-Protein coupled recptors (GPCRs) of high pharmacological relevance. The cell lines have been generated by stable transfection of CHO-K1 cells and subsequent clonal selection. They have been specifically validated for a read-out in homogenous time-resolv…
Cell Membranes - Custom Preparation of Cell Membranes from CCS Cell Culture Service Preparations membranes from cell which are expressing a target receptor, transporter or ion channel at a high density are a useful tool in drug research. Embedded in a membrane fragment or vesicle the proteins remain in a functional native confirmation. Ligand binding assay and functional GTP-gammaS assays can be performed with these preparati…
