Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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Resolution ctDx FIRST Assay

Agilent Technologies

Agilent Resolution ctDx FIRST is a liquid biopsy NGS assay optimized for cancer genomic profiling. ctDx FIRST is an FDA approved companion diagnostic to KRAZATI™ (adagrasib) for the detection of KRAS G12C in non-small cell lung cancer (NSCLC) and provides tumor mutation profiling for single nucleotide variants (SNVs) and deletions in the EGFR gene.

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Seahorse XF T Cell Metabolic Profiling Kit

Agilent Technologies

The Agilent Seahorse XF T Cell Metabolic Profiling kit allows for robust and accurate measurements of both glycolytic and mitochondrial activities in T cell populations, providing a complete picture of T cell energy metabolism. These measurements can be linked to antitumor properties of T cell therapy products and are therefore valuable in designing and optimizing therapy development processes to improve T cell persistence or…

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Agilent Seahorse Analytics

Agilent Technologies

Agilent Seahorse Analytics is the newest data analysis application for Agilent Seahorse XF Analyzer products. Seahorse Analytics is built in the cloud, meaning there is no software for you to install, update, or manage. Learn how Seahorse Analytics can make your data analysis experience easier and more enjoyable. Register for a free account and start uploading your assay result files now.

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Seahorse XF Plasma Membrane Permeabilizer

Agilent Technologies

The Agilent Seahorse XF Plasma Membrane Permeabilizer (PMP) is a proprietary reagent that permeabilizes intact cells in culture. It selectively targets the cellular plasma membrane while leaving the mitochondrial membrane intact. This selectivity enables the detailed characterization of key components in mitochondrial function including transporters, enzymes, and electron transport chain complexes.

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Seahorse XF Hu T Cell Activation Assay Kit

Agilent Technologies

Agilent Seahorse XF Hu T Cell Activation Assay Kit measures human (Hu) T cell activation response within several minutes of stimulation using Seahorse XF Analyzers. This is accomplished via measuring proton efflux rates (PER) associated with glycolytic pathway-dependent energy production, and is built on the principle that T cell activation is accompanied by a rapid switch in cellular energy production and intermediate demand…

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Seahorse XF Palmitate Oxidation Stress Test Kit and FAO Substrate

Agilent Technologies

The Agilent Seahorse XF Palmitate Oxidation Stress Test Kit provides validated reagents to measure long chain fatty acid oxidation (FAO) via assessing changes in oxygen consumption (OCR) in intact cells. The kit includes the XF Palmitate-BSA FAO Substrate, L-carnitine, etomoxir, as well as oligomycin, FCCP, and rotenone/antimycin A to determine the intrinsic rate and capacity of a cell to oxidize palmitate in the absence or l…

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Cell Culture & Imaging Microplates

Agilent Technologies

Agilent offers a new microplate product line to support cell culture and imaging. These high-quality polystyrene products provide superb optical clarity and comply with ANSI standards for compatibility with automated processing systems. TC surface treatment enhances cell attachment while the included lid maintains a sterile growth environment with low risk of cross-contamination. The product designs feature easy stacking, alp…

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SureSelect Cancer CGP Assay ​

Agilent Technologies

SureSelect Cancer CGP assay offers comprehensive genomic profiling for solid tumors. This pan-cancer NGS panel enables detection of somatic variants, including single nucleotide variants (SNVs), copy number variants (CNVs), insertions/deletions (indels), translocations (TLs), gene fusions, and the immuno-oncology biomarkers TMB (tumor mutational burden) and MSI (microsatellite instability).

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Cary 3500 Compact UV-Vis Spectrophotometer

Agilent Technologies

The Cary 3500 Compact UV-Vis is a double beam spectrophotometer featuring new and unique measurement capabilities that can be deployed in regulated environments. The system performs ambient and temperature-controlled experiments with air-cooled Peltier temperature control, and it accurately analyzes low volume samples—providing in-depth analysis by collecting up to 250 data points per second. The xenon flash lamp—complete with…

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xCELLigence RTCA HT-BioTek BioSpa8 – Screening Model

Agilent Technologies

Integration of the xCELLigence Real Time Cell Analyzer (RTCA) HT instrument with the BioTek BioSpa 8 automated incubator expands the screening throughput of your RTCA HT instrument to eight 384-well plates. Label-free high-throughput xCELLigence Real-Time Cell Analysis is ideal for screening viral mediated cytopathic effects (CPE), neutralizing antibodies, antibody-dependent cytotoxicity (ADCC), and compound mediated cytotoxi…

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SureSelect DNA Capture Arrays

Agilent Technologies

Designed for smaller studies, the SureSelect DNA Capture Arrays complement Agilent's in-solution SureSelect Target Enrichment System, which is designed for medium to large-scale NGS studies of tens through thousands of samples, including automated high-throughput workflows.

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SureSelect Custom RNA

Agilent Technologies

Agilent’s market leading SureSelect platform provides a complete portfolio of catalog and custom products, providing the flexibility you need from discovery to follow-up studies. Agilent’s custom solutions offer the only available method for target enrichment of RNA, allowing you to target your regions of interest using our free web portal SureDesign. Custom solutions are available for DNA and RNA target enrichment. • The only…

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eArray

Agilent Technologies

eArray is a web-based application that enables you to harness the flexibility of Agilents SurePrint oligo manufacturing technology in the creation of custom microarray designs and oligo libraries.  eArray, free to all registered users, allows you to create assays that are specific to your research needs. Create custom microarray designs for Gene Expression, microRNA, Model Organisms, CGH, ChiP-on-chip, and DNA Methylation.Crea…

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Human Gene Expression Microarrays

Agilent Technologies

The Agilent SurePrint G3 Human GE 8x60K Microarrays offer the same high sensitivity and accuracy provided by the earlier generation arrays but adds the benefits of extended coverage, greater throughput, and increased cost savings. The new SurePrint G3 Human GE 8x60K Microarrays and Human GE 4x44K v2 Microarrays are based on updated transcriptome databases for mRNA targets, while the SurePrint G3 arrays also include probes for…

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Juno™

Standard BioTools Inc.

Targeted NGS library preparation, gene expression and genotyping. Increase productivity and efficiency with automated, cost-effective, and easy-to-use workflows for targeted DNA next-generation sequencing (NGS) library preparation, gene expression analysis and genotyping by allele-specific PCR.

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C1™ System

Standard BioTools Inc.

Automated platform for single-cell omics and multi-omic research using solid-state microfluidics. C1 with integrated fluidic circuits (IFCs) enables the preparation of single-cell templates for total RNA sequencing and multi-omic applications such as preparing mRNA and DNA and mRNA and protein from the same isolated and imaged single cell.

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CTA Protein Array

SomaLogic

Profiling against cancer antigens. Using the CTA Protein Array, Sengenics can quantify autoantibodies against more than 200 clinically relevant cancer testis antigens. These are tumor antigens normally expressed in germ cells but not in adult somatic tissues. In cancers, this regulation can be disrupted, resulting in CTA expression in tumors. The CTA array is ideal for research related to cancer immunotherapy.

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