Drug discovery > Basic Research Products & Reviews

Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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Applied Biosystems 3500 Genetic Analyzer

Thermo Fisher Scientific

We set a new standard in capillary electrophoresis with the 8-capillary 3500 and 24-capillary 3500xL Genetic Analyzers. The 3500 8-capillary platform can run a wide variety of applications —including de novo sequencing and resequencing (mutational profiling)—as well as microsatellite analysis, MLPA™, LOH, MLST, AFLP® and SNP validation or screening. The majority of applications can be run on a single polymer and capillary arra…

4.5/5.0
|11 Reviews

NimbleGen MS 200 Microarray Scanner

The NimbleGen MS 200 Microarray Scanner is the first scanner optimized to unleash the full potential and capture the complete picture from NimbleGen DNA microarrays. The MS 200 offers 2 micron resolution and heightened sensitivity to achieve high data quality and confident results from high-density NimbleGen microarrays of today and tomorrow. Critical to the the workflow, NimbleScan and SignalMap software are included to ana…

5.0/5.0
|1 Review

Crimpenstein™ Electric Crimper / Decapper

WHEATON

Electrify your crimping and decapping operations with the new innovative Wheaton Crimpenstein™. The innovative Crimpenstein™ is engineered to improve productivity and efficiency where vials are capped with aluminum seals. The AC powered Crimpenstein™ crimper/decapper provides fast, consistent results with a simple push of a button. The ability to change jaw-sets offers an unmatched level of flexibility and economy for appli…

5.0/5.0
|1 Review

ZEISS LSM 780 Laser Scanning Microscope

ZEISS Research Microscopy Solutions

LSM 780 - Obtain Quantitative Information About Your Cells and Individual Molecules. The sensitivity of LSM 780 is quite simply outstanding. The GaAsP detector achieves 45 percent quantum efficiency compared to 25 percent typically by conventional PMT detectors. This results in accurate details and contrast-rich images of the challenging specimens you encounter in your live cell imaging.The system’s illumination and detection…

4.6/5.0
|9 Reviews

Attune™ Acoustic Focusing Cytometer

Thermo Fisher Scientific

The Attune™ Acoustic Focusing Cytometer gives you both high sensitivity and high throughput. With this technology you can control your sample concentration, the flow rate, the number of photons you detect, the length of your experiment, the number of samples you run, and more. And you can get the most out of your cells with dependable results. What’s more, the Attune™ instrument makes all of this easy to do. Key features:…

4.5/5.0
|3 Reviews

Solaris qPCR Gene Expression Master Mix

Thermo Fisher Scientific

Solaris qPCR Master Mix has been developed in conjunction with Solaris qPCR Gene Expression Assays for quantification of DNA and cDNA. Optimal qPCR results using probe detection chemistries can be achieved by using this same system of qPCR products. Optimized Solaris qPCR Master Mixes have been developed to ensure the best possible Solaris assay performance. In addition to enhanced performance, these optimized reagents offer…

4.5/5.0
|2 Reviews

G-actin / F-actin in vivo assay kit

Cytoskeleton Inc.

The most reproducible and accurate method of determining the amount of filamentous actin (F-actin) content versus free globular-actin (G-actin) content in a cell population is to use Western blot quantitation of F-actin and G-actin cellular fractions. The general approach is to homogenize cells in F-actin stabilization buffer, followed by centrifugation to separate the F-actin from G-actin pool. The fractions are then separate…

5.0/5.0
|1 Review

GFP Variant Vectors

Takara Bio

These bacterial expression vectors carry the gene for either GFP (wild type Aequorea victoria green fluorescent protein) or GFPuv (a GFP variant optimized for maximal fluorescence when excited by UV light [360–400 nm]) and are driven by the lac promoter. These vectors can also be used as a source of the indicated fluorescent protein coding sequences. The fluorescent protein gene can be amplified by PCR or readily excised using…

5.0/5.0
|1 Review

Lipofectamine™ RNAiMAX Transfection Reagent

Thermo Fisher Scientific

Lipofectamine™ RNAiMAX Transfection Reagent from Invitrogen   Invitrogen Lipofectamine™ RNAiMAX Transfection Reagent is a proprietary RNAi-specific cationic lipid formulation that offers the highest transfection efficiencies on the widest variety of cell types for siRNA gene knockdown experiments. With Invitrogen Lipofectamine™ RNAiMAX Transfection Reagent you will get: • Superior transfection efficiency requiring…

4.6/5.0
|6 Reviews