Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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Fluorescence Microtiter Microplates

Thermo Fisher Scientific

Thermo black and white microplates help you to optimize your assay performance in fluorescent applications. These microplates are designed for use with light emitting markers, having carefully selected pigments to eliminate cross talk and reduce background signals of your assays. Different binding characteristics and formats are available. Product detail:Microtiter Microfluor microplates and universal/enhanced binding plates…

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Clear Bottom Microtiter Microplates

Thermo Fisher Scientific

These clear bottom microplates are sterile and thus ready to cultivate bacteria and fungi. TC treatment makes them perfect for mammalian tissue culture with no need for chemical treatments. They are individually packaged with lid and their unique design helps to eliminate cross-talk. The microplates are perfect for microscopic viewing and also suitable for top and bottom reading instruments. Low background fluorescence and lum…

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UV Microtiter Microplates

Thermo Fisher Scientific

Thermo UV microplates are designed specially for your applications adapted for the UV wavelength area. The performance is optimal down to at least 220 nm with fairly low absorbance background. Thus nucleic acid and protein determinations using this microplate made of UV light transmitting material are enabled at 260/280 nm. The microplate is also compatible with any standard microplate reading or liquid handling device. Produ…

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Coated Microtiter Microplates

Thermo Fisher Scientific

Streptavidin coated wells of the BioBind microplate offer biotin mediated binding for small or hydrophilic molecules. This surface is ideal for e.g. peptides, oligonucleotides and DNA hybridization assays. The streptavidin-biotin bond is extremely strong and stable, and utilizing this system problems associated with steric hindrance during the binding procedure can be avoided. Product detail: BioBind - Streptavidin Coated…

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ORCA-Flash4.0 Camera

Hamamatsu Corporation Camera Products Group

Hamamatsu’s brilliantly designed ORCA-Flash4.0 is truly a game changer in the world of scientific imaging. Built on a revolutionary new Gen II sCMOS detector, the ORCA-Flash4.0 is the first sCMOS camera that challenges the performance of all CCD, EM-CCD, and Gen I sCMOS cameras. With its combination of low noise and high quantum efficiency, the ORCA-Flash4.0 delivers unprecedented sensitivity as well as high dynamic range, bla…

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SeqSolve Integromics

Integromics

SeqSolve™ is an advanced and user-friendly software solution for the tertiary analysis of Next Generation Sequencing (NGS) data. By integrating state-of-the-art bioinformatics methods into one-click analysis workflows, SeqSolve is the only software able to provide scientists with such a combination of both cutting edge and intuitive user experience. Its Click And Go® technology enables the automatic processing of the data, whi…

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Corning® 5 mL Internal Threaded Polypropylene Cryogenic Vial, Self-Standing with Round Bottom

Corning Life Sciences

5 mL capacity with round bottom Self-standing design Black graduations and larger marking spots for easier filling and sample identification Manufactured from polypropylene to withstand temperatures to -196°C Silicone washer for a secure seal Vials may be color coded with inserts (see Cat. No. 430499) Special base design allows vials to be locked into cryogenic rack and tray (Cat. No. 430525 or 431131) for single-hande…

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Arrayed BAC library

Bio S&T

An arrayed or non-arrayed BAC library is the preferred choice for downstream applications such as hybridization screening; full-genome sequencing; BAC end sequencing or physical mapping projects. Amount of clones received is based on a guaranteed coverage and 120Kb average insert size. HMW DNA isolation and QC by HMW DNA enzymatic digestion are included. Deliverables for ARRAYED BAC library: Clones will be arrayed and amplifie…

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Screened BAC library

Bio S&T

A pooled BAC library is an invaluable tool for PCR-screening. It allows for the easy retrieval of BAC clones of interest. This type of library is especially useful when genome size is large and creating an arrayed library is cost-prohibitive. We typically construct a minimum 5X BAC library and BAC clones are then pooled and distributed in 96-well plates. Each well will contain about 400-500 original BAC clones. HMW DNA isolati…

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Normalized cDNA libraries

Bio S&T

Our cDNA libraries feature full-length-enriched and high quality size-fractionated cDNA. cDNA library construction is usually done in slightly-modified versions of pBluescript or pcDNA3.1. Insert sizes will range from about 0.5Kb to 4Kb. Concerning QC steps, we evaluate the average insert size, empty clone rate and clone concentration/tube before shipping out. We always provide a gel picture of randomly selected clones showing…

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APAgene™ GOLD Walking Kits

Bio S&T

APAgene™ GOLD Genome Walking Kits are designed to rapidly and reliably amplify unknown genomic DNA using our patented APA technology: 1. Isolate unknown genomic sequences flanking transgenes (including T-DNAs, gene traps, transposons), sequence-tagged sites (STSs) or expressed sequence tags (ESTs). 2. Isolate localized sequences flanking known sequences from large clones and genomic DNAs. 3. Sequence insert ends of large clone…

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ASH cDNA Subtracted Library

Bio S&T

ASH is APA-based, full-length-enriched, single-stranded cDNA subtraction hybridization library. - ASH cDNA subtraction is full-length-enriched and independent of PCR suppression. - ASH cloning is directional and does not involve normalization. - ASH method provides non-exponential amplification before subtraction because double-stranded cDNA is not required. - ASH method has a better subtraction effect because 1) a high ratio…

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RNA Isolation for Sequencing

Bio S&T

Bio S&T's high-quality RNA can be used directly for NxGen RNA sequencing as well as other downstream applications that require optimal-quality RNA such as quantitative real-time RT-PCR, microRNA cloning and amplification and Northern blotting.

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Retroviral Research Products

Bio S&T

Bio S&T is the only commercial provider of highly purified human tRNAs. RNA is most widely used as the primer of retroviral reverse transcriptases. The 3’ end of the tRNA binds to the complementary binding site on the viral RNA therefore initiating reverse transcription. 1. tRNALys3 is the primer of HIV-I, HIV-II, SIV and FIV. 2. tRNALys1,2 are the primers of BLV, HTLV-I and II, SSV, FLV, VV, CAEV, MPMV, SMR and EIAV. 3. tRNAT…

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RealTime Ready Assays

RealTime ready Custom RT-qPCR Assays and Panels Get a head start on your gene expression analysis with function tested assays for all annotated human, mouse, and rat genes Achieve high specificity using intron-spanning assays based on short hydrolysis LNA-substituted Universal ProbeLibrary (UPL) Probes.  Rely on stringently RT-qPCR-tested assays that are compliant with MIQE (Minimum Information for Publication of Quantitati…

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x-tremeGENE DNA Transfection Reagents

Improve your cell analysis and use our powerful new transfection reagents: Efficiently transfect a broad spectrum of cells, including difficult-to-transfect cell lines and tumor cell lines. Generate physiologically relevant results using low cytotoxic reagents. Avoid time-consuming optimization using fast, reliable protocols.

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SeqCap EZ Human Exome Library v3.0

Discover More, Sequence Less Built upon the NimbleGen Sequence Capture empirically optimized probe design algorithm with high efficiency uniformity of capture1, and now with expanded coverage of coding exons, SeqCap EZ Exome v3.0 offers increased performance. Capture the most comprehensive picture of the human exome with SeqCap EZ Exome Library v3.0. Based on the latest database builds and offering a 64Mb sequence capture, Seq…

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DILI Assay

Thermo Fisher Scientific

The Thermo Scientific ToxInsight Drug Induced Liver Injury Assay Cartridge for the ToxInsight IVT Platform offers a new multi-parameter cell-based assay to determine the risk of liver injury by chemicals being tested for new drugs or for consumer products safety assessment. The ToxInsight DILI Cartridge is for identifying compound hepatotoxicity by simultaneous detection of multiplexed targets, including cell loss, nuclear DNA…

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EPP (Endocrine Profiler Panel)

Thermo Fisher Scientific

The Thermo Scientific ToxInsight Endocrine Profiler Panel offers a complete solution for consumer products companies needing to comply with regulatory Reproductive Toxicity testing requirements. Traditional methods of assessing endocrine disruption in vitro measure single targets in homogeneous formats and have a record of low predictive power. The Thermo Scientific ToxInsight Endocrine Profiler Panel leverages our proven tech…

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Advanced High Resolution 2-colour Fluorescence Microarray Scanner: InnoScan 910

Innopsys

Performance, Resolution, Speed. With its new detection system, the InnoScan 910 has the highest resolution and reading speed on the market. This user-friendly, two-color scanner is the ideal tool for reading current and future high-density microarrays.With outstanding sensitivity and signal-to-noise ratio derived from its highly regarded photometric properties, the InnoScan 910 is a confocal detection scanner fitted with 2 ex…

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Analysis Software for Microarray Images: Mapix

Innopsys

Simple, User-friendly, High performance.Mapix is characterised by its ease-of-use. It is a standard in the field of segmentation (automatic searching for microarray spots). Mapix has the most up to date requirements to browse data from microarray experiments quickly, with a high level of reliability and optimised productivity.Mapix can be customized, allowing users to add their own functions using its exclusive plug-in system.…

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TIGRIS® DTS™ System

GEN-PROBE Inc.

Absolute Automation Is True Walk-Away Freedom for: ■ Sample Preparation ■ Sample Processing ■ Results Analysis Only the TIGRIS® DTS™ System, with Absolute Automation, automates all phases of molecular diagnostics testing from sample preparation, amplification, and detection to reporting results. Integrating the TIGRIS DTS System with APTIMA® assay kits for nucleic acid testing (NAT) offers true freedom from hands-on processing…

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R'ALF: Autoclaveable Benchtop Fermentor

BiOENGiNEERiNG

The ultimate standard for autoclaveable bench-top fermentor systems Comes with all necessary controls and accessories for fermentation or cell culture Can operate in continuous, batch, and fed-batch modes Size range: 2.0-7.0 L Option to run up to 6 fermentors at a time from one station with our state-of-the-art BiOSCADA software system: offering countless options for control strategy, process engineering, and data manag…

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NLF: Small Pilot Fermentor

BiOENGiNEERiNG

The flexible & mobile laboratory fermentor for cultivation excellence: Designed for laboratory or small-scale production purposes In-situ sterilizable, with electrical heating system or steam heat exchanger As a modular system with glass or steel cylinders, can readily adapt to a wide variety of needs with minimum hassle Can operate in continuous, batch, and fed-batch modes Available as a cGMP fermentor for small-s…

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