Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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VeroFect

OZ Biosciences

VeroFect™ is a powerful reagent dedicated to the transfection of Vero cells. This lipid -based transfection reagent is issued from the revolutionary Tee-Technology and achieves up to 50-55% transfection efficiency. The complexes formed by DNA and VeroFect™ reagent have an exceptional capacity in destabilizing cell membranes, allowing the delivery of important DNA amounts into cells. VeroFect™ was specifically designed to obtai…

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Corning® 96-well Black/Clear Flat Bottom Polystyrene Not Treated Microplate, 25 per Bag, without Lid, Nonsterile

Corning Life Sciences

Bottoms are 60% thinner than conventional polystyrene plates, resulting in lower background fluorescent and enabling readings down to 340nm Designed to reduce well-to-well crosstalk during fluorescent assays Can be used for both top and bottom reading instruments Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the i…

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Portrait Heat Sealer

REMP AG Laboratory Automation

The REMP Portrait Heat Sealer is a completely electro-mechanical, thermal sealing instrument that does not require any air or vacuum to operate. This versatile and efficient instrument accommodates deepwell, assay, PCR, and standard microplates with only a minor adapter change. The REMP Portrait Heat Sealer uses any of the various rolls of REMP’s Thermo-Seals, most of which are resistant to DMSO, as well as, other solvents and…

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Corning® 96-well EIA/RIA Clear Flat Bottom Polystyrene High Bind Microplate, Individually Wrapped, without Lid, Nonsterile

Corning Life Sciences

High binding surface binds medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions Binding capacity of approximately 500ng of mouse IgG/cm2 Ideal for immunoassays Certification results for each lot are made available upon request by contacting local Corning Life Sciences office Recommended working volume of up to 75 to 200 µL Conforms to standard microplate footprint and dimensions Wi…

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Antibody Array Nanoscale Buffer Kit

Clontech Laboratories, Inc.

Extract and label proteins from extremely limited sample sizes The first commercially available nanoscale buffer kit for antibody arrays Minimal background for high signal-to-noise ratios Optimized for use with the Clontech™ Ab Microarray 500 Kimberly Milner and Dmitry Bochkariov, Ph.D. The Clontech™ Antibody Array Nanoscale Buffer Kits designed for those who have limited amounts of sample and want to assay hundreds…

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Immunoassays for the Hemostasis Factors

Aniara Corporation

The Zymutest line of Elisa kits are ready to use. Complete line of Enzyme Immuno assays, using 96 well microElisa plates, disposable in 12X8 well strips. Made for the exploration of plasma factors, fibrinolysis, autoimmunity, and markers of thrombotic diseases. They all include calibrators and controls.

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H-9500, high performance TEM

Hitachi High Technologies America, Inc.

The H-9500 is a high performance TEM featuring a single crystal LaB6 electron source. This allows 0.102 nm crystal lattice resolution and 0.18 nm point to point to be achieved. The instrument features a low magnification operating mode of x200 to x500 and a high magnification mode with zoom from x1000 to x1,500,000. Fully PC-controlled, the instrument has an icon-driven user interface and is designed for very fast operation. W…

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OptoScan Monochromator

Cairn Research Ltd

The Optoscan monochromator from Cairn Research is the only instrument of its type to offer control of both centre-wavelength and bandwidth with millisecond time resolution. Combined with Cairn signal processing modules and optical hardware it forms the heart of a powerful and flexible microfluorescence system. Alternatively it can be readily integrated into commercial imaging systems, or custom controlled for bespoke applicati…

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Thermo Scientific Fermentas PCR Master Mix (2X)

MBI Fermentas

Thermo Scientific* Fermentas PCR Master Mix is a 2X concentrated solution of Taq DNA Polymerase, dNTPs and all the components required for PCR, except DNA template and primers. This pre-mixed formulation saves time and reduces contamination due to a reduced number of pipetting steps required for PCR set up. The mix is optimized for efficient and reproducible PCR. ■ Convenient—Taq DNA Polymerase in a ready-to-use mix ■ Fast—sa…

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antibody, mouse clone 31A3

MorphoSys UK Ltd (Formerly Biogenesis Ltd)

Product Type: antibody. Immunogen: native, from brain. Host: mouse. Type: monoclonal. Clone: 31A3. Subclass: IgG1. Format: affinity purified Ig. Preparation: prepared by Protein A chromatography. State: liquid. Buffer: PBS buffer, pH 7.2, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.Cross reactivity Reacts with PGP 9.5 from human and rat. Tissue reactivity Stains neuronal cell bodies and axons in the CNS and peripher…

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antibody, mouse clone 10-11

MorphoSys UK Ltd (Formerly Biogenesis Ltd)

Product Type: antibody. Immunogen: native, from plasma. Host: mouse. Type: monoclonal. Clone: 10-11. Subclass: IgG1-k. Format: affinity purified Ig. Preparation: Protein A chromatography. State: liquid. Buffer: borate buffered saline, pH 8.4, 0.1% sodium azide. Storage: aliquot and store at -20°C.Cross reactivityDoes not react with C4c. Does not cross react with cow, cat, dog, guinea pig, mouse, rabbit, sheep or rat.Specificit…

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antibody, goat: purified

MorphoSys UK Ltd (Formerly Biogenesis Ltd)

Product Type: antibody. Immunogen: native. Host: goat. Type: polyclonal. Format: purified Ig. Preparation: Ammonium Sulphate fractionation. State: liquid. Buffer: PBS buffer, pH 7.2, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.ImmunohistochemistryThis antibody, when tested in the serum format, has given variable results in IHC. The purified product has not been evaluated for this application by Biogenesis.ELISAIn a…

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antibody, sheep: serum, rat

MorphoSys UK Ltd (Formerly Biogenesis Ltd)

Product Type: antibody. Immunogen: native, purified. Host: sheep. Type: polyclonal. Format: serum. Preparation: neat. State: liquid. Buffer: without preservatives. Storage: aliquot and store at -20°C.RIA 1/4K - 1/20K (125 I) IHC to be determined Cross reactivity rat GH 100% rat ACTH Suggested protocol Overnight (16-24 hr) equilibrium assay with DAB/PEG separation. 100 µl standards, 100 µl tracer (18,000 cpm) and 200 µl primary…

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antibody, mouse clone 5B6/6

MorphoSys UK Ltd (Formerly Biogenesis Ltd)

Product Type: antibody. Immunogen: native. Host: mouse. Type: monoclonal. Clone: 5B6/6. Subclass: IgG1-k. Format: affinity purified Ig. Preparation: Protein A chromatography. State: liquid. Buffer: PBS buffer, pH 7.4, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.Cross reactivityReacts with human, porcine, bovine, rat and mouse insulin and proinsulin.SpecificityEpitope recognised is different from that identified by 5…

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Myelin Basic Protein (MBP) antibody, mouse clone V/h1

MorphoSys UK Ltd (Formerly Biogenesis Ltd)

Product Type: antibody. Immunogen: BSA conjugate. Host: mouse. Type: monoclonal. Clone: V/h1. Subclass: IgG1. Format: affinity purified Ig. Preparation: Protein A chromatography. State: liquid. Buffer: PBS buffer, pH 7.2, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.RIA titre to be determined ELISA titre to be determined IHC titre to be determinedCross-reactivityReacts with pure MBP from sheep, rabbit, guinea-pig and…

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Keratin 3/12 antibody, mouse clone AE5

MorphoSys UK Ltd (Formerly Biogenesis Ltd)

Product Type: antibody. Immunogen: native, see notes. Host: mouse. Type: monoclonal. Clone: AE5. Subclass: IgG1. Format: affinity purified Ig. Preparation: Ion Exchange chromatography. State: liquid. Buffer: PBS buffer, pH 7.2, 0.1% Sodium Azide. Storage: aliquot and store at -20°C.Cross reactivityReacts with bovine and rabbit snout and lip epithelium. Reacts with some oral mucosa epithelium. This antibody also reacts with rab…

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Collagen 1, antibody, rabbit: affinity

MorphoSys UK Ltd (Formerly Biogenesis Ltd)

Product Type: antibody. Immunogen: native, from placenta. Host: rabbit. Type: polyclonal. Format: affinity isolated. Preparation: affinity chromatography. State: lyophilised. Buffer: contains mannitol, dextran and salts. Storage: store at -20ºC, aliquot reconstituted at -20ºC.Cross reactivityHuman collagen type III SpecificityThis antibody reacts with native and heat denatured collagen type I. Human plasma proteins do not inte…

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Genom 2005

GSA - Software Development and Analytics

The program "Genom 2005" is a feature rich and user friendly tool to analyse array-experiments.Key Features:Analyse all AffyMetrix-Arrays (cDNA-Arrays or similar technologies could easily be integrated as well) Normalisation of Raw-Data Many additional gene information (official Gennames, Location, Function prediction, Sequences, Database-references (Gene-Ontology, InterPro, SwissPROT ,EMBL, ENSEMBL, LocusLink, OMIM, GeneBank.…

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