Drug discovery > Basic Research Products & Reviews

SB-431542 is a potent and selective inhibitor of activin receptor-like kinase ALK5, the TGF- β1 receptor. 

Cell Line Origin Mouse BALB/c monocyte macrophage Cell Line Description Derived from a tumour in a female BALB/c mouse. Cell line produces IL-5 and lysozyme. Application J774A.1 cell line has been used to test the cytotoxicity of [1,2,3]triazolo[1,5-a]pyridinium salts (having leishmanicidal activity) from triazolopyridines. It has also been used to determine the antitrypanosomatid activity of flavonoid glycoside…

From human samples to induced pluripotent stem cell (iPSC) lines to screening, choose the steps we can do for you!

The Endosafe ® nexgen-PTS™ is a rapid, point-of-use handheld spectrophotometer that uses USP/BET-compliant disposable cartridges for accurate, convenient, and real-time endotoxin testing, glucan concentration determination, and Gram identification. With its small benchtop footprint, the Endosafe ® nexgen-PTS™ is ideal for small to mid-size pharmaceutical companies and compounding pharmacies that want a portable, real-time t…

Combining flexible throughput capabilities with a streamlined workflow, the Applied Biosystems ™ QuantStudio ™ 12K Flex system takes you from targeted discovery through confirmation and screening, all on a single platform.

Fast- The all-new Hirox platform delivers fast operation and faster processing speeds.  Easy-  The premier choice in user-friendly software, a digital microscope has never been easier to operate.  High quality- Images saved and taken with the KH-8700 are delivered with ultra-fine detail.   

The faster Vi-CELL BLU automates the Trypan Blue Dye Exclusion method for cell viability analysis.

Raman multimodal microscope 

The LIVE/DEAD Sperm Viability Kit provides a novel fluorescence-based assay for analyzing the viability and fertilizing potential of sperm by fluorescence microscopy or flow cytometry. Membrane-permeant SYBR® 14 nucleic acid stain labels live sperm with green fluorescence, and membrane-impermeant propidium iodide labels the nucleic acids of membrane-compromised sperm with red fluorescence.

The Applied Biosystems® MicroAmp® Optical Adhesive Film reduces the chance of well-to-well contamination and sample evaporation when applied to a microplate. Features include: • Pressure-sensitive adhesive provides a tight seal over every well • Will not interfere with sample reading • Press-N-Seal: Align properly to the plate, then press to seal • Easy to apply-will not stick to your glove Prevent loss of precious…

Upgrade your crystallization screens with the New Industry Standard: The Crystal16 benchtop crystallization system.

The RX-5000α (alpha)-Plus features improved accuracy over the RX-5000α-Plus, with Brix ±0.010 and nD ±0.00002. Is has a thermo-module to control temperature, a constant temperature water bath is not necessary.It displays the top-and-bottom-limit-bar for your set control range. The RX-5000α (alpha)-Plus features improved accuracy over the RX-5000α-Plus, with Brix ±0.010 and nD ±0.00002. Is has a thermo-module to control temp…

4K Ultra-high accuracy microscope

The Heidelberg Retina Tomograph (HRT) is based on fast and reproducable topographic measurements. The glaucoma module premium edition provides high-resolution two- and three-dimensional images of the optic nerve head, the retina module of the retina and the rostock cornea module of the cornea.  Rostock Cornea Module With the Rostock Cornea Module (RCM) the HRT becomes a high-resolution confocal cornea microscope to recei…

The CryoPod™ Carrier is a truly portable device that enables -150°C sample transport over short distances. It is safe, reliable and maintains the cold chain. Integrated monitoring, alarms, and logging ensure cryogenic sample protection for over 3 hours.

The BioStore III Cryo provides the best in class automated storage solution for cellular products and other materials requiring storage temperatures below glass transition (Tg)

The BX51WI is the ideal tool for physiological experiments such a patch clamping and intravital microscopy.

prep GEM Universal is a widely-used, adaptable reagent ideal for rapid DNA extractions from life science samples such as blood, saliva, cell culture, and tissue (including ear punches, tails, and insect). The heat-driven extraction is done in a single-tube with no harsh chemicals or additional steps so there is no loss of DNA, enabling extractions from very low sample volume. The kit is perfect for CRISPR/Cas9 gene editing a…

Fully automated 2 microplate analyser.

The CytoSMART Lux2 is a compact inverted microscope for bright-field time-lapse imaging. It works from inside any standard CO2-incubator and can be used in routine cell culture processes. The CytoSMART Lux2 provides a small and easy solution for time-lapse imaging. Monitor cell proliferation, motility and morphology for hours up to weeks at a time.

mMESSAGE mMACHINE® kits are designed for the in vitro synthesis of large amounts of capped RNA. Capped RNA mimics most eukaryotic mRNAs found in vivo, because it has a 7-methyl guanosine cap structure at the 5' end. mMESSAGE mMACHINE® kit reactions include cap analog [m7G(5')ppp(5')G] in an ultra high-yield transcription reaction. The cap analog is incorporated only as the first or 5' terminal G of the transcript because its s…

Immobilon ® ECL Ultra Western HRP Substrate is an ultra-sensitive reagent with long signal duration for the detection of horseradish peroxidase (HRP)-labeled antibodies on western blots. The intense signal created permits sensitive detection at the mid-to-low femtogram range using x-ray film or digital imaging systems.

Phenol-free total RNA isolation from micro-sized samples!

Pkg of 25, clear shell/clear well 3-side (Row H, Column 1, and Column 12) barcoded PCR plate to fit most instruments, rigid 2-component design

This HTRF kit detects changes of cAMP accumulation in response to Gs coupled GPCR activation or inhibition.