Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.
The Cell Motility V2 BioApplication is a advanced image analysis algorithm for measuring the overall motility of cells. It quantitates total distance traveled by each cell exposed to growth factor or compound for a quantiative assessment of cell motility. The V2 version includes advanced analytical capabilities such as population analysis and object segmentation. This application has been biologically validated, enhancing c…
Spot Detector V2 performs measurements of number, size, and other features of spots in cells. It is an easy-to-use and essential component of any image analysis software suite. This tool is excellent for measuring receptor internalization and trafficking, cell proliferation and counting, Analyzing populations. This application has been biologically validated, enhancing confidence in your image-based data. Available for the…
The Neurite Outgrowth V2 BioApplication is a streamlined image analysis algorithm for morphological analysis of neurite outgrowth. Utilizes fluorescent images of neurons and neurites stained for tubulin to quantitate the number and length of neurites in a population of cells. This application has been biologically validated, enhancing confidence in your image-based data. Available for the Cellomics ArrayScan VTI, ArrayScan x…
Cyto-Cell Membrane Translocation V2 is a multi-channel image analysis algorithm for analysis of targets that translocate from cytoplasm to cell membrane. It utilizes colocalization of fluorescent markers to report whether the target is co-localized to the membrane, and reports cells' behavior relative to a control population. This application has been biologically validated, enhancing confidence in your image-based data. A…
GPCR Signaling V2 is a high-content image analysis application for quantitation of the activation of G-protein coupled receptors. Classifies cells into different phases based on pattern of receptor complex distribution and reports details of and percentage of cells with Type A and Type B recycling activity. This application has been biologically validated, enhancing confidence in your image-based data. Available for the Cel…
The Multiparameter Apoptosis Kit comprises three spectrally distinct fluorophores that label cellular targets to allow assessment of cell health by looking at several biological parameters. This kit specifically labels nuclei, f-actin, and mitochondrial mass/potential in cells. The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied to any imaging system. Available in Evaluation Size (Five…
The Multiparameter Cytotoxicity 1 Kit comprises three spectrally distinct fluorophores that label cellular targets to allow assessment of cell health by looking at several biological parameters. This kit contains indicators for nuclei, permeabilized cells, and lysosome mass/pH. The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied to any imaging system. Available in Evaluation Size (Five…
Neuroscreen-1 is a neuronal-like cell line optimized for screening. It is a subclone of PC12, a widely used cell line derived from rat pheochromocytoma cells that serves as a standard model system for neurons. Neuroscreen-1 cells display several substantial advantages over PC12 cells, including 50-80% faster growth, no tendency toward cell aggregation, high and accelerated responsiveness to NGF (measurable neurites within 2…
MIAS-2 readers are a new generation of HTS microscopy readers with an unequaled blend of sensitivity, flexibility and speed. They are designed to cover the throughput and flexibility needs at multiple phases across the R&D value chain. In drug discovery R&D, applications include target identification, target validation, assay development, high throughput screening, hit-to-lead, deep pharmacology and ADMET. Unique features…
