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ZORBAX 80Å StableBond columns are made using bulky, patented, unique silanes that sterically protect the siloxane bond. Acid labile endcapping reagents are not used. The result is vastly improved column life and extraordinary chemical and temperature stability in the pH 1–6 range for a wide variety of phases (SB-Aq, SB-C3, SB-CN, SB-Phenyl, SB-C8, and SB-C18). Excellent peak shape is expected for many basic compounds because…
ZORBAX 80Å StableBond columns are made using bulky, patented, unique silanes that sterically protect the siloxane bond. Acid labile endcapping reagents are not used. The result is vastly improved column life and extraordinary chemical and temperature stability in the pH 1–6 range for a wide variety of phases (SB-Aq, SB-C3, SB-CN, SB-Phenyl, SB-C8, and SB-C18). Excellent peak shape is expected for many basic compounds because…
ZORBAX 80Å StableBond columns are made using bulky, patented, unique silanes that sterically protect the siloxane bond. Acid labile endcapping reagents are not used. The result is vastly improved column life and extraordinary chemical and temperature stability in the pH 1–6 range for a wide variety of phases (SB-Aq, SB-C3, SB-CN, SB-Phenyl, SB-C8, and SB-C18). Excellent peak shape is expected for many basic compounds because…
Eclipse Plus columns provide the ultimate in performance for silica-based columns. Peak shape for the Eclipse Plus is excellent for the most challenging basic compounds, improving efficiency and resolution with these sample types.
Agilent Mass Profiler Professional (MPP) software is a powerful chemometrics platform designed to exploit the high information content of MS data and can be used in any MS-based differential analysis to determine relationships among two or more sample groups and variables.
The Agilent MassHunter METLIN Metabolomics Database and Library enable streamlined metabolite identification to facilitate understanding of global metabolic changes that can occur in a biological system. Available as a comprehensive database of metabolites (PCD) that optionally includes MS/MS spectra (PCDL).
The 1260 Infinity II Preparative Fraction Collector is optimized for laboratories performing semipreparative-scale purification of milligram to low gram quantities with typical flow rates between 4 and 100 mL/min. The module features the full set of collection modes and is compatible with a wide variety of trigger sources. SBS plates and four different tube sizes with various lengths are supported.
The 1260 Infinity II Manual Injector is an HPLC valve for manual injection of samples at pressures up to 600 bar. It is supplied with a baseplate, which is dimensioned to match the footprint of all 1260 Infinity modules. The 1260 Infinity II Manual Injector is a compact, affordable solution for sample injection.
The diode array design of the 1260 Infinity II Multiple Wavelength Detector offers very low detector noise (less than ±7 µAU) for precise quantification of trace levels, regardless of the number of signals recorded. Over a wavelength range from 190 to 950 nm, simultaneous detection of up to eight compound-specific wavelengths for optimum selectivity is provided. High-speed UV detection with up to 120 Hz data rates keeps pace w…
The 1260 Infinity II Preparative Binary Pump is an affordable high-pressure gradient pump for LC purification. The pump offers a dynamic flow rate range from 1 to 50 mL/min at up to 420 bar, allowing workflows on columns from 9.4 to 30 mm inner diameter.
The 1260 Infinity II Variable Wavelength Detector enables highest productivity with fast analysis at up to 120 Hz data rates. Even more sample information can be acquired in dual-wavelength mode. Time-programmable wavelength switching provides optimum sensitivity and selectivity for your applications.
These Gilson engineered caps produce a positive pressure seal with the needle in the Gilson ASPEC, ASPEC XL and ASPEC XL4 solid phase extraction systems.
Conversion of cartridge-based methods to an automation friendly 96-well format has never been easier or faster. The same trusted silica-based sorbents in Bond Elut cartridge products are now available in the streamlined Bond Elut 96-well plates. Bond Elut 96 components are specially formulated to offer superior cleanliness, flow reproducibility, and reliability.
Bond Elut 96 Square-well Plates are specially designed to offer superior cleanliness, flow reproducibility, and reliability, ensuring trouble-free, high throughput operation. Conversion of cartridge-based methods to an automation-friendly 96-well plate format has never been easier or faster.
Bond Elut AccuCAT cartridges are mixed bed SPE cartridges consisting of a strong cation exchange (SCX) and a strong anion exchange (SAX) sorbent packed into one bed. AccuCAT is effective for the extraction of acidic, basic, and neutral analytes from urine and other biological samples. AccuCAT is particularly effective for catecholamine extraction from biofluids.
Bond Elut adapters fit on top of any Bond Elut cartridge and contain a female Luer fitting that accommodates the tip of another cartridge.
Alumina, like silica, is an extremely polar sorbent. The alumina surface tends to be slightly more stable under high pH conditions than unfunctionalized silica. The small particle size of the Bond Elut Alumina range ensures high extraction efficiency even when small bed masses are used.
Due to the methyl group and subsequent low carbon load, Bond Elut C1 is the least retentive of all alkyl group bonded phases for nonpolar compounds. However, due to the extensive endcapping of this sorbent to mask polar silanol activity, retention, and elution of polar and multifunctional analytes can still be achieved.
Bond Elut EWP is based upon standard particles size silica but with 500 pores to allow more efficient extraction of large molecules (>15,000 MW), which are typically excluded from standard porosity silica phases.
Bond Elut C18 OH is a nonendcapped version of the octadecyl bonded phases that enables the silanols on the silica surface to be more active. This low-load C18 has well-controlled silanol activity that permits the fractionation of metabolites and enhances retention of basic compounds compared to an endcapped C18. The pore size makes it a good choice for peptide extraction.
Bond Elut C2 is a fairly nonpolar sorbent because of the short chain length of the functional group. C2 is often used during the process of method development if analytes are retained too strongly on a C8 or C18 phase. The polarity of C2 is slightly lower than a cyano phase for polar interactions.
Bond Elut C8 is very similar in property to C18, but is not as retentive for nonpolar compounds due to its shorter hydrocarbon chain and therefore reduced carbon loading. C8 is an excellent replacement for C18 when analytes are too strongly retained for effective elution.
Bond Elut Carbon cartridges are packed with ultrapure graphitized carbon particles that have been optimized for the absorption of pigments in food, fruits and vegetables, and small organic residues in wastewater. The powerful retention mechanisms of these products are appropriate for a broad range of analytes. In addition, careful manufacturing techniques result in lower carbon fines on the wall of the device.
CBA is a midpolarity sorbent and weak cation exchanger (pKa 4.8). It can be used with a wider range of counterions than lower pKa sorbents like SCX, and will demonstrate easier elution of quaternary amine functionalized analytes.
Bond Elut Cellulose columns utilize a pure microgranular cellulose powder that is packed between two, 20 µm polyethylene frits. The cellulose phase is very stable over a wide pH range and contains an extremely low metal content (Fe and CU content less than 5 ppm).
