Drug Discovery & Development Products & Reviews

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Through extensive research, experimentation, and clinical trials, experts in the field of drug discovery and development identify promising biopharmaceutical or pharmaceutical drug candidates, optimize their efficacy and safety profiles, and navigate regulatory processes for eventual market approval. From innovative therapies to groundbreaking treatments, this dynamic scientific field plays a pivotal role in revolutionizing medicine and saving lives.

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Biotage® VacMaster™ Manifolds

Biotage

Biotage® VacMaster™ Sample Processing Manifolds allow samples to be processed simultaneously under vacuum. Easy-to-use vacuum controls provide excellent sample flow control, leading to reproducible, reliable extraction conditions.

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Biotage® Lysera Bead Mill Homogenizer

Biotage

Lyse or homogenize the toughest samples in seconds. Biotage® Lysera is an advanced, easy-to-use bead mill homogenizer designed for rapid, efficient grinding, lysing, and homogenizing of diverse biological samples. With a compact front-loading design, 99 programmable settings, temperature monitoring, and a wide range of accessories, it delivers reproducible results for any sample type without downtime between runs.

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Biotage® Extrahera™ Peptide

Biotage

Biotage® Extrahera™ Peptide automates sample workup with precision and ease. Designed for synthetic labs, it enables automated solid phase extraction (SPE) and catch-and-release purification of up to 96 samples simultaneously. Positive pressure processing and complementary consumables ensure consistent, high-purity peptide samples free of catalysts and excess reagents.

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EVOLUTE® SPE Columns and Plates

Biotage

EVOLUTE® Sample Preparation products feature advanced water-wettable polymer-based sorbents that deliver clean extracts and consistent analyte recovery for accurate LC-MS/MS quantification. Designed to minimize ion suppression and matrix effects, they provide reliable performance across a wide range of acidic, basic, and neutral compounds.

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Biotage® PeptiPEC-96 High Throughput Kit

Biotage

Biotage® PeptiPEC-96 High Throughput Kits streamline peptide purification with the automated PurePep® Easy Clean (PEC™) catch-and-release strategy. Purify 96 peptides simultaneously while removing impurities efficiently for cleaner, higher-quality peptide libraries.

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Biotage® PeptiRen-96 Well-plate

Biotage

Biotage® PeptiRen-96 well plates streamline peptide library workflows by enabling simultaneous post-synthesis clean-up of 96 crude peptides. Featuring reversed-phase media optimized for peptide SPE, they provide an efficient, automatable solution for rapid enrichment and preliminary screening.

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synthWAVE microwave synthesis system

Milestone

The Milestone synthWAVE is designed for safe, reliable and reproducible scale-up of microwave enhanced chemical reactions. The synthWAVE is capable of higher temperature and pressure than any other microwave reactors. Milestone synthWAVE features the unmatched Single Reaction Chamber (SRC) patented technology that ensures scale, reaction screening, highest temperature and pressure. It is able to handle single or multiple react…

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flexiWAVE Microwave Synthesis System

Milestone

The new Milestone flexiWAVE overcomes the limitation of conventional microwave synthesis reactors, as it consists of a single microwave platform that, in combination with specific accessories, allows the chemists to perform classic glassware and high pressure synthesis, as well as solid-phase reactions.

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Carterra Ultra™

Carterra

Disruptive technology for the characterization of small molecules and fragments. With enhanced sensitivity, expanded thermal options, and advanced microfluidics, the Carterra Ultra™ platform is our most sensitive instrument for interrogating multiple proteins and off-target binding in parallel.

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Carterra LSA-XT

Carterra

Disruptive Technology for Screening and Characterization. Enhanced sensitivity and fast data collection rate build upon unmatched capabilities in throughput and enable assays such as TPDs/PROTAC®s, kinase, cytokines, DELs, and protein:protein inhibitors.

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AptaFluor™ SAH Methyltransferase Assay

BellBrook Labs

The AptaFluor® SAH Methyltransferase Assay Kit enables ultra-sensitive, direct detection of SAH—the universal product of methyltransferase reactions—using a riboswitch-based TR-FRET format. With no coupling enzymes required, it delivers high signal-to-background, Z’ ≥ 0.7, and is fully HTS-compatible for drug discovery and inhibitor screening.

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Lead Discovery Services

BellBrook Labs

BellBrook Labs’ Lead Discovery Services deliver expert support for hit-to-lead efforts. From inhibitor screening and potency profiling to residence-time, mechanism-of-action, and selectivity studies, their team tailors efficient enzymatic assays to your program—accelerating lead advancement with precision and flexibility.

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Transcreener® cGAMP cGAS Assay

BellBrook Labs

The Transcreener® cGAMP cGAS Assay Kit offers mix-and-read fluorescent detection of cGAMP—the product of cGAS activity—with no coupling enzymes required. Available in FP or TR‑FRET readouts (far-red tracers minimize interference), it’s HTS-ready (Z’ ≥ 0.7), automation-compatible, and validated on 96‑, 384‑, and 1536‑well formats for enzyme kinetics, SAR, and inhibitor screening.

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