Drug discovery > Drug Manufacturing Products & Reviews

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Products, services, reviews and techniques used in pharmaceutical product scale-up, formulation, shipping and manufacturing processes.

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CytoPak™ GMP Human IL-2 Protein

ACROBiosystems

CytoPak™ GMP Human IL-2 Protein comes in sterile, closed-system packaging for seamless integration into ex vivo clinical production. The medical-grade multilayer bag features weldable tubing options, allowing direct connection to GMP media bags. Its liquid form eliminates the need for reconstitution, enhancing safety and ease of use.

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ActiveMax® Streptavidin μBeads, premium grade (for cells)

ACROBiosystems

ActiveMax® Streptavidin μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm with streptavidin on its surface. Streptavidin is a tetrameric protein providing 4 high-affinity biotin binding sites, which make it possible to fast prepare and customize your own sterile protein/antibody coupled beads for cell based assay, cell sorting, cell therapy process development and manufacturing use.

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CytoPak™ GMP Human IL-7 Protein

ACROBiosystems

CytoPak™ GMP Human IL-7 Protein comes in sterile, closed-system packaging for seamless integration into ex vivo clinical production. The medical-grade multilayer bag features weldable tubing options, enabling direct connection to GMP media bags. Its liquid form eliminates the need for reconstitution, enhancing safety and ease of use.

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GMP Human IFN-gamma Protein

ACROBiosystems

Interferon-gamma (IFN-gamma ), also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine. IFN-gamma is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells.

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GMP Human DLL4 Protein, Fc Tag

ACROBiosystems

ACRO offers two GMP-grade DLL4 proteins, GMP-DL4H27 (Flagship Product) and GMP-DL4H28 (Complementary Product), designed for iPSC cell culture and differentiation applications. While both proteins undergo similar manufacturing processes with minor procedural variations, they are strategically positioned to address distinct user needs.

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GMP Human IL-2 Protein

ACROBiosystems

Recombinant IL-2 is widely used in cell culture for the expansion of T cells. In cell culture, IL-2 is a frequently used cytokine for the proliferation, differentiation, and increased antibody secretion of B cells as they transform into plasma cells in vitro.

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GMP Human Laminin 521 Protein

ACROBiosystems

GMP Human Laminin 521 Protein supports feeder-free PSC culture, maintaining growth and stemness without differentiation for over 10 passages. It’s produced in a GMP-compliant, animal-free process with strict QC testing to ensure quality. Designed for clinical research, it enables a seamless transition from preclinical studies to cell therapy applications.

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GMP Human FGF basic Protein

ACROBiosystems

Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2 and plays an important role in many immunological diseasesreticulum. The dominant mechanism of IL-15 action is known as transpresentation.GMP IL-7 and GMP IL-15 are commonly used in combination for ex vivo expansion of T cells for cellular therapies.

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GMP Human IL-4 Protein

ACROBiosystems

Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a monomeric, approximately 13 kDa‑18 kDa Th2 cytokine that shows pleiotropic effects during immune responses.Due to its role in the differentiation of certain immune cell types, IL-4 is commonly used in combination with other growth factors to transform induced pluripotent stem cells into dendritic cells in high numbers.

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XcytoMatic® High-throughput cell density analyzer

ChemoMetec

The XcytoMatic® 40 (XM40™) is a high-throughput cell density and viability analyzer that can run 24 samples in under 14 minutes. The variation between cell counts for these samples is under 3%. If scale-out and scale-up is a concern, you can trust each XM40™ instrument in your production to deliver the same quality results.

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FlowCam LO

Yokogawa Fluid Imaging Technologies, Inc

Innovative particle characterization with FlowCam® LO combines flow imaging microscopy (FIM) and light obscuration (LO) into a single analytical solution. Beyond the compendial light obscuration method to fulfill USP <787> and <788> requirements, flow imaging microscopy provides an orthogonal method for quality control of subvisible particulate matter.

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VisualAI

Yokogawa Fluid Imaging Technologies, Inc

VisualAI™, an add-on module for VisualSpreadsheet 6, is a pre-trained, AI-driven image analysis module that recognizes images of biopharmaceutical aggregates captured on any FlowCam 8100 or FlowCam LO instrument. VisualAI is a powerful tool for quantifying protein aggregate and silicone oil droplet content in protein-based drug products.

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Chameleon - Automated Platesealing Station

Kbiosystems

Heat applied automated plate sealer and stacker Automated SBS format plate stacking system All SBS format micro well plates Cycle time per complete plate seal cycle stack to stack from 20 seconds Foli present sensing Plate Heights from 9 - 48mm high Touch panel Light weight system only 12kgs Full error diagnostics Seal time from 0.1 to 9.9 seconds

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Evolve® Process Columns

Astrea Bioseparations

Evolve ® Process Columns have been designed specifically for use in biopharmaceutical applications. Available in eight diameters, Evolve ® Process Columns provide cost effective, scalable, high performance technology suitable for use in both pilot and production scale chromatographic processes.

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Phi-TEC I

H.E.L. Group

The Phi-TEC I is an adiabatic calorimeter that enables the characterization of thermal runaway hazards during process development and scale-up. The Phi-TEC I replicates industrial (large volume) conditions on a lab-scale, enabling thermal runaway hazards to be characterized safely and efficiently.

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