Drug discovery > Lead Discovery Products & Reviews

A successful packing material from the start: LiChrosorb® is one of the most successful and reliable packing materials used in HPLC for more than 25 years and documented in literature in the form of several thousand applications. The totally porous irregular particles are finely classified in the 5, 7 and 10 µm range. LiChrosorb® offers the complete programme of non-polar derivatives (RP-8, RP-18, RP-select B) polar derivativ…

Spherical silica carrier for constant results on high level: LiChrospher® are reliable and versatile traditionally produced spherical silica carrier. LiChrospher® silica carrier are available with different modifications. For the LiChrospher® RP-phases a selectivity and performance guarantee makes sure that these parameters remain constant form batch to batch and from year to year. The polar modified phases LiChrospher® CN, L…

LiChrospher® CN is a versatile HPLC sorbent based on spherical silica particles possessing both polar and hydrophobic properties. LiChrospher® CN may be used as weakly hydrophobic sorbent in reversed phase chromatography or as polar sorbent in normal phase chromatography.

LiChrospher® DIOL is a versatile HPLC sorbent based on spherical silica particles possessing both polar and hydrophobic properties. LiChrospher® DIOL may be used as weakly hydrophobic sorbent in reversed phase chromatography with some limitations or as polar sorbent in normal phase chromatography. LiChrospher® DIOL is also suitable for exclusion chromatography.

A versatile sorbent for both reversed phase and straight phase chromatography: LiChrospher® NH2 is a versatile HPLC sorbent based on spherical silica particles possessing both polar and hydrophobic properties. LiChrospher® NH2 may be used for normal phase chromatography, reversed phase chromatography and for ion exchange chromatography. Typical applications are the separation of carbohydrates (mono-, di- and oilgosaccharides)…

LiChrospher® PAH is a highly efficient and selective HPLC column especially designed for the high resolution separation of 16 PAH (polycyclic aromatic hydrocarbons) according to EPA 610 and 550 + benzo(e)pyrene + perylene. LiChrospher® PAH is based on a special modified RP-18 silica gel to achieve highly resolved PAH separations. LiChrospher® PAH can be used for both, the isocratic separation of 6 PAH according to the German…

For reproducible reversed phase separation: LiChrospher® RP-phases are reliable and versatile traditionally produced spherical silica carrier with reversed phase properties. They are well suited for the chromatography of acidic, neutral and weakly basic compounds, substances found frequently in all analytical fields. A selectivity and performance guarantee makes sure that these parameters remain constant form batch to batch a…

Excellent separations even with basic compounds: LiChrospher® RP-select B is a versatile reversed phase sorbent based on spherical silica particles with excellent properties for the determination of basic substances, but with still good properties for the determination neutral and acidic substances. LiChrospher® RP-select B is optimised in order to prevent any secondary interactions with basic substances and guarantees that…

High-resolution separations of peptides and tRNA molecules: LiChrospher® WP 300 RP-18 is a highly selective and reliable HPLC column for the separation of peptides and low molecular weight proteins. LiChrospher® WP 300 RP-18 enables the tailing-free separation of basic compounds and is excellently suited for the separation of tRNA molecules. High recovery rates are achieved, especially in the case of highly hydrophobic pepti…

Cellpuri® is a disposable chip that enriches cells without the use of centrifugation method. Cells are being separated using the rheological phenomenon inside the microchannels where the cell suspension pass through to filter out waste medium and collect the enriched cells in the outlet.

Flare™ is a ligand-based and structure-based drug design platform. Through high-resolution 3D visualization and in-depth analysis of target structures and potential ligands, Flare enables users to optimize and prioritize new molecules efficiently and effectively.

Flare™ enables the production of high-resolution 3D graphics of your ligands and proteins for publications and communication of results.

Flare™ FEP enables research chemists to refine docking results, making the right structure-based design choices for lead optimization with confidence.

Spark™ is a powerful scaffold hopping and bioisosteric replacement solution that generates highly innovative ideas for your project to explore chemical space and escape IP and toxicity traps.

Blaze™ is an advanced virtual screening platform enabling you to dramatically increase your wet screening hit rate at a fraction of the cost.

Torx® connects medicinal chemistry teams and CROs across the DMTA cycle to drive productivity in small molecule discovery in a secure cloud-based platform.

Cresset Discovery is a premier computational chemistry CRO with a proven track record delivering high impact drug discovery projects. From ideation to synthesis and biological results, their expert CADD scientists are the best at what they do. Working alongside you from the ground up, they apply the best in silico techniques, and give expert advice and guidance, to accelerate your assets through the pipeline.

Simplify your omics research

The new standard of excellence in quantitative metabolomics profiling

Unraveling the complexity of disease

Efficient workflows for busy laboratories

Metabolomics in nutrition, microbiome, and disease

Expert support from study design to actionable results

Mass Spectrometry Software for Spectral Interpretation and Component Characterization

Biotherapeutics Discovery