Drug discovery > Lead Discovery Products & Reviews

These Corning® syringe filters have acrylic copolymer housings, female Luer lock inlets and male Luer slip outlets. Polyethersulfone (PES) membranes provide the fastest flow rates, low protein binding and low extractables 100% integrity tested, sterile and certified nonpyrogenic and noncytotoxic Manufactured in accordance with ISO 9001 standards

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Untreated microplates have a binding capacity of approximately 100 to 200ng IgG/cm² Without lids, lids supplied separately Total volume is…

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Total volume is 190 µL; recommended working volume of up to 25 to 125 µL Conforms to standard microplate footprint and dimensions Without l…

This microplate has half the growth area of a standard 96 well plate Flat bottoms with 190 µL total volume White walled plates enhance luminescent signals and have low background luminescence and fluorescence Opaque walls to prevent well-to-well crosstalk Nonreversable lids with condensation rings to reduce contamination Sterilized by gamma radiation and certified nonpyrogenic Bulk packed 20 per bag

The Direct Connection UNIGUARD allows the guard cartridge outlet to be directly placed against the analytical column inlet frit. Product detail: We recommend all analytical columns are protected by a guard cartridge, which is replaced on a regular basis. The ID of the analytical column determines the correct ID for the guard cartridge. We offer 10x1, 10x2, 10x3, 10x4mm guard cartridges in all our stationary phases to ensur…

The Javelin guard design is a one-piece format that can be installed without wrenches and requires no holder, which allows quick and easy replacement. Product detail: We recommend all analytical columns are protected by a guard column or cartridge, which is replaced on a regular basis. The ID of the analytical column determines the correct ID for the guard, so we offer 1.0, 2.1, 3.0 and 4.0 diameter Javelin guard columns in…

MultiSEP™ solid phase extraction wells from Thermo Electron offer robust and reproducible sample preparation and pre-concentration on a routine basis.Wells are available in pre-assembled plate format or as individual wells to allow customisable plates to be assembled by the user.Sorbent packings include the ever-popular silica based bonded phases and also include novel and unique chemistries for specialised applications. Multi…

HyperREZ™ columns are specially designed for analysis of organic acids, alcohols, saccharides and carbohydrates. They employ a polymeric support with ligand exchange groups. The ligand exchange resins contain highly sulfonated cation exchange resins that have Group I, Group II or transition metals associated with the chromatographic surface.HyperREZ™ columns are based upon a polymeric resin that shows stability from pH 1 to 14…

White walled plates enhance luminescent signals and have low background luminescence and fluorescence Flat bottoms with 360 µL total volume Recommended working volumes of 75 to 200 µL Treated for optimal cell attachment Without lids, lids supplied separately Sterilized by gamma radiation and nonpyrogenic Individual alphanumeric codes for well identification Bulk packed 25 per bag

BioBasic 8 Columnso   Improved reproducibility, efficiency and column lifetimeso   Range of stationary phases to optimize selectivityo   Powerful resolution, even on short column lengths Product detail:BioBasic 8 columns provide exceptional reliability for separations of proteins, peptides, and other biomolecules through a combination of high purity silica and reproducible, stable bonding.  The proprietary bonding procedure en…

BetaMax Acid Columns o   High surface area area and bonded phase coverage for maximum retention, even in high percentage organic conditionso   Chemistries for acidic compounds Product detail: For alternative selectivity to traditional alkyl phases, we recommend you try the polar embedded phase BetaMax columns. The stationary phase contains urea groups embedded within the C12 chain, which extra interactions with samples to…

BETASIL C18 Columnso   Broad range of particle sizes and phases for wide method development optionso   High surface area and phase coverage for reproducibility and sharp peak shapes Product Detail BETASIL columns are based on 100Å pore size, fully deactivated type B silica to ensure sharp peaks and excellent reproducibility for the analysis of a wide range of compounds. The 100Å pore size gives a higher concentration of statio…

BetaBasic 4 Columnso   Excellent peak shapes for basic compoundso   Superb stability at both low and high pH Product detail:BetaBasic 4 columns are based on a 150Å pore size, fully deactivated type B pure silica to ensure sharp peaks and excellent reproducibility for the analysis of basic compounds.  Due to stable bonding chemistry and excellent surface coverage, BetaBasic 4 columns show excellent peak shape for basic compound…

Hyperbond™ is a cost effective alternative to µBondapak (a trademark of Waters Corporation). It is based on an irregular silica with 10µm particle size.

o   100% porous graphitic carbon with very different selectivity to reversed-phase silica columnso   Exceptional retention of very polar compoundso   Separation of structurally similar compoundso   Stable from pH 1 to 14 at high temperatures in a wide range of solvents Product detail: Hypercarb is a unique material for HPLC manufactured by Thermo Hypersil-Keystone. Hypercarb consists of fully porous spherical carbon particle…

o  Separate hydrophobic and ionic compounds in a single runo  Select from two mixed mode phases, using either cation or anion exchange combined with C18o  Retention of compounds is optimized using mobile phase pH, ionic strength and percent organic Product detail: Hypersil Duet columns are an ideal choice for unknown compounds and metabolism studies, as they can separate hydrophobic and ionic compounds in a single analysis…

The Hypersil SAX is recommended for analysis of small organic molecules and organic acids. Product detail: Hypersil SAX is a strong anion exchange column, which is typically used for  analysis of small organic molecules and organic acids. As the columns are based on the first generation classical 120Å pore size silica they are not recommended for analysis of biomolecules. For new methods we recommend trying our latest ion…

Thermo Electron Hot and Cool Pockets™ offer unbeatable value in coulmn temperature control. The pockets are small and light weight yet offer precise temperature control. Hot pockerts heat from 5 to 85 oC with a temperature accuracy of ±2oC over the entir range, and a temperature stability of ±0.1Oc. Hot Pockets™ and Cool Pockets™ are not available within the European Union at the present time. We apologise for any inconvenien…

Bottoms are 60% thinner than conventional polystyrene plates, resulting in lower background fluorescent and enabling readings down to 340nm Designed to reduce well-to-well crosstalk during luminescent assays Can be used for both top and bottom reading instruments Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the i…

A new screw cap that has been introduced for HP users, to enable them to use a screw top vial on a robotic arm autosampler.

Feature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) Certified DNase- and RNase-free Total volume is 320 µL; recommended working well volume is 75 to 200 µL Without lids; lids, sealing mats and tapes supplied separately

Easy Ion DeterminationHamilton PRP-X100 ion chromatography columns are the easy way to separate inorganic ions. You can use these columns with any existing HPLC or ion chromatograph to easily determine anions in almost any sample matrix including: air, water and soil. PRP-X100 columns provide a number of benefits.Better than Wet Chemical MethodsAnyone using wet chemical or colorimetric methods will find that ion chromatography…

Hamilton RCX-10 And RCX-30 Columns for the Anion Exchange Separation of CarbohydratesHamilton RCX-10 carbohydrate analysis columns are designed for the isocratic and gradient separation of carbohydrates. Samples containing two or three carbohydrates, for example Ice Cream can be quickly separated isocratically while more complex samples like Corn Syrup, require gradient elution to fully resolve all the oligomers (DP1 to DP7).…

Cisbio's HTRF® KinEASE™ platform has expanded to include a universal assay for tyrosine kinases. The HTRF KinEASE TK assay is based on our patented HTRF technology and uses a unique tyrosine peptide substrate in combination with a Europium-labeled monoclonal antibody. The HTRF KinEASE™ TK assay has been validated on 59 tyrosine kinases to-date including both receptor and cytoplasmic TKs. A proprietary substrate stabilizing buf…