Drug discovery > Lead Discovery Products & Reviews

Nanospray kit introduced at HPLC 2001, Beyond Genome SAN JOSE, Calif. and CAMBRIDGE, Mass., June 19 -- Thermo Finnigan, a Thermo Electron (NYSE:TMO) business, and New Objective, Inc., which both supply essential products to proteomics research markets, are teaming up in a strategic supply agreement to introduce the NanoFlow Solutions Kit, which will greatly simplify the use of low-flow nanospray ionization for proteomics. The…

Single & double end fittings in stainless steel & PEEK collared connectors

HyperGEL columns are packed with porous polymeric beads with a precise pore size distribution so that solutes are accurately separated according to molecular size.High efficiency HyperGEL columns provide a minimum of 50,000 plates/metre for 5µm particle size. The columns are available for aqueous (HyperGEL AP) or organic (HyperGEL OP) separations.HyperGEL OP columns are offered in 7 pore sizes and 2 particle sizes to test mole…

Get maximum loading and efficiency from your preparative columns. Achieve high loading with Thermo Electron phases and column sizes up to 50mm ID and 250mm length. Our column packing and silica expertise ensures our preparative columns achieve optimum efficiency and lifetimes.Our BETASIL™ and Hypersil™ 100 phases are ideal for preparative separations. We recommend the separation is proven using an analytical scale column packe…

o   Excellent retention and alternative selectivity for polar compoundso   Completely stable under 100% aqueous conditionso   Ideal for LC/MS applications Product detail: AQUASIL C18 columns provide more retention for difficult-to-retain polar compounds due to a unique hydrophillic end-capping.  The combination of a moderate coverage C18 group and an additional polar group gives new selectivity compared to a traditional C18.…

HyPURITY ADVANCE Columns  - offer exceptional chromatographic performance and is ideal for high throughoput laboratories with complex and variable sample types. Product detail: HyPURITY ADVANCE contains a polar amide group embedded within a C8 chain, and is fully endcapped. The columns are based on our metal free HyPURITY silica and, compared to other phases, produces a competely new selectivity. A polar functiona…

Hypersil BDS C18 Columnso   Sharp peaks and improved symmetry for basic compoundso   Value and performance from a globally referenced columno   Long column lifetimes with excellent column-to-column and batch-to-batch reproduciblity Product detail:Hypersil BDS C18 receives a special base deactivation treatment during silica material manufacture to reduce silanophilic activity. Hypersil BDS C18 is endcapped and suitable for chro…

o  Based on ultra pure 190 Å pore size silica for analysis of small molecules to proteinso  Extensive quality control tests to ensure the ultimate in reproducibility and performanceo  Unbeatable peak shapes for all sample typeso  Select from five phases for a wide range of selectivity options Product detail: HyPURITY C18 columns are based on the latest in silica technology - HyPURITY silica, which has less than 10ppm total m…

To obtain precise information about the structure of synthetic peptides and proteins, it is imperative to achieve good separation (see illustration).Hypersil Amino acid columns have been developed for this purpose with excellent reproducibility and the highest reproducibility using high grade 5µm particle size silica with a high surface area. Achieve resolution of complex sequences of amino acids with sharp peak shapes.Hypersi…

High efficiency  capillaries for high performance, sensitive separations 500, 320, 180, 100 & 75µm ID capillaries  Availabe in a wide range of Thermo phases Rugged sleeved design for robustness 180µm ID flexible KAPPA for FinniganTM ProteomeX™ Workstation Product detail: Capillary and nanobore columns are ideal for applications which require high sensitivity. However, in order to take full benefit of the improvement i…

Universal Assay for Serine/Threonine KinasesCisbio's line of HTRF® KinEASE™ STK kits are based on our patented HTRF® technology and can be used as a universal tool for assessing Serine/Threonine kinase activity. These assays use a proprietary antibody and a choice of three biotinylated substrates developed by Upstate to rapidly produce high quality kinase results. Our HTRF KinEASE™ STK kits have been validated on more than 107…

Xiril’s Neon 150 serves high throughput needs and is the perfect choice for your targeted solutions, with unmatched options and flexibility on a relative small platform. Up to two pipetting arms with 8 independent pipetting channels each or even a 96 channels head can take over automated reformatting, dilution series, PCR-Setup, archiving, extractions, hit picking etc., while you are free for other jobs. The Neon technology cr…

Providing a complete research management environment that allows chemists to manage the entire lifecycle of their research, ChemBook (E-WorkBook for chemistry) extends the functions of the core E-WorkBook solution with specific tools that support and simplify the day-to-day research of medicinal and synthetic chemists. Chemists can combine any contextual data along with the details of the reaction undertaken, Microsoft® Office…

Mounts up to Six Detectors and Five Injectors Ambient to 400oC Temperature Programmable Column Oven Dimensions: 19" wide x 13.5" high x 14.5" deep Implement virtually any EPA or ASTM method The Model 8610C Gas Chromatograph is our most versatile and popular model. While it is very compact next to comparable laboratory GCs from other manufacturers, it is large enough and flexible enough to perform an amazing variety o…

Run assays up to 5 times faster than a conventional HPLC. Increase mass spec sample throughput by a factor of 5. Eliminate dead time in your analysis and cut solvent usage by 99 percent. Achieve all this and more with the ExpressLC-100 system. TheExpressLC-100 system is a single-channel HPLC with binary solvent delivery, high pressure gradient mixing, variable volume injection, UV absorbance detection, and PC-based instrument…

High Throughput SonicationFeatures: Stand-alone instrument 96, 384, and 1536 interchangeable disposable pinned lid technology Plate shuttle allows for direct integration with pick & place robotics. Variable power settings between 1 and 1150 watts. Variable sonication time intervals from 0.1 to 20 seconds.

Aitken Scientific provide a service of software and hardware integration to a broad range of clients. These clients are mainly based in pharmaceuticals, engineering, scientific research, instrumentation and manufacturing. We work with small start-ups to major international companies delivering solutions across the world. We have worked with one major pharmaceutical company for many years on over 40 projects and had very positi…

Application The Cell Proliferation Reagent WST-1 is designed to be used for the nonradioactive, spectrophotometric quantification of cell proliferation and viability in cell populations using the 96-well-plate format. It can be used for: Measurement of cell proliferation in response to growth factors, cytokines, mitogens, and nutrients Analysis of cytotoxic and cytostatic compounds, such as anti-cancer drugs and other ph…

The basic system is a counter with sample trays holding either 40 (5x8) 20 ml vials or 96 (8x12) 7ml vials. The counter has a pneumatic arm which is loading the samples to the detector chamber. The counter has a unique three PMT detector which enables Triple to Double Coinciencidence Ratio counting. This enables easy determination of sample counting effiency without any external or internal standard. The counter will have an o…

The Finnigan NEPTUNE is a high performance Multicollector-ICPMS with high mass resolution capabilities for high precision isotope ratio measurements. It combines highest sensitivity and highest stability for all elements with the latest multicollector technique. High mass resolution on all detectors is the key to discriminate against molecular interferences. Product detail: Multicollector ICP-MS The design of the Finnigan…

The Finnigan TRITON gives the ultimate precision for isotope ratio measurements on solid samples. It uses a proven thermal ionization source and has a unique variable multicollector platform which can be configured with Faraday detectors and/or miniaturized ion counting detectors for smallest sample sizes. Typical applications are dating of geological samples as well as control of isotopic compositions of nuclear materials.…

The Finnigan DELTAplusAdvantage is the economical stable isotope ratio MS for all dual-inlet and continuous-flow applications not requiring continuous-flow D/H capability. It is fully automated, very sensitive and has an amplifier dynamic range. Product detail: The Stable Isotope Engine The DELTAplus Advantage builds on the proven robustness and performance of the DELTAplus, while adding new capabilities through completel…

Mass Frontier 4.0 provides you with the tools required to transform mass spectral data into results – fast! The new Mass Frontier excels at predictive fragmentation and data management. Mass Frontier provides a mechanistic understanding of fragmentation schemes using proprietary mass spectral interpretation algorithms. In addition, relationships within datasets can be explored using various types of classification such as PCA,…

Xcalibur™ software is a flexible Windows® based data system that provides instrument control and data analysis for the entire family of Thermo Electron mass spectrometers and related instruments. Xcalibur's wide range of functionality and ability to integrate third-party control provides the tools to perform a wide range of applications. Several specialized software modules have been designed to work with Xcalibur to meet…