Drug discovery > Lead Discovery Products & Reviews

Waters offers scalable prep systems, from the AutoPurification™ System for high-throughput fraction collection from hundreds of samples, to simple low-pressure mixing systems for purifying a few samples a day. Take the complexity out of purification with our versatile solutions that are capable of purifying micrograms to multiple grams, in a single system that can be configured to automatically process hundreds of samples. Key…

The ACQUITY UPLC® Evaporative Light Scattering (ELS) Detector is designed specifically for optimal UPLC®/ELS performance in a small footprint. When your analytes have poor to no UV/Vis response, or don’t ionize well by mass spectrometry, the ACQUITY UPLC ELS Detector with the ACQUITY UPLC System lets you analyze more molecules (including sugars, triglycerides, phospholipids, antibiotics, and natural products) in a single analy…

Xevo TQ-S tandem quadrupole mass spectrometer - designed for the most demanding quantitative UPLC/MS/MS applications. The ultimate in tandem quadrupole performance allows you to achieve unrivalled sensitivity and robustness, available to everyone due to the accessibility of the Xevo platform. The Xevo TQ-S gives you class leading sensitivity and robustness, qualitative information when you need it most and accelerated metho…

The ACQUITY UPLC H-Class PLUS Bio System delivers the benefits of UPLC's resolution, sensitivity, and throughput in a system purpose-built for the analysis of proteins, peptides, nucleic acids, and glycans.

The 2545 Quaternary Gradient Module is a four solvent, low pressure mixing gradient pump (up to 150 mL/min) that serves as a solvent delivery device for purification systems. Features: • Four solvent gradient selection • Control from MassLynx, Empower, or console allowing scale up via a familiar software interface • Interfaces to a variety of detectors and peak fraction collectors for optimum purifications • Allows UV or MS di…

UPLC Technology Extends To Two Dimensions For chromatographers who require additional capabilities to increase their speed of analysis, gain sensitivity and selectivity, and perform orthogonal separations, ACQUITY UPLC® Systems can meet these needs by controlling multiple valves and pumps for 2D separations. The resolution, sensitivity, and throughput benefits of UPLC® Technology are even more important in 2D applications. Wat…

The PAL µSPE cartridge stands for a miniaturized and robust SPE technology that allows reliable automation and reduction of used sample and solvent without compromising performance. The µSPE has therefore emerged as a new standard for extraction, purification, concentration or filtration for automated environmentally friendly analysis processes.

With Millicell inserts, attachment or suspension cells can access media from both their apical and basolateral sides. Cell growth, structure, and function more closely mimic what occurs in vivo. In addition, Millicell inserts make it possible to study both sides of the cell monolayer.Millicell inserts are available for 24-, 12-, or 6-well plates. The inserts are easily prepared for SEM and TEM visualizing techniques, and they…

ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, extracting up to 400 µL aqueous sample.

Isolera, a compact flash purification system with intelligent features, enables chemists to easily achieve better separations. The patented TLC-to-gradient feature automatically creates elution gradients and suggests cartridge and sample size. Collect fractions using two wavelengths, adjust the flow rate from 1 to 200 mL/min as needed and use up to four solvents in a single gradient, for maximum purity and yield.

PhyTip® Columns offer automated, flexible and scalable solution for biomolecule separation. The PhyTip® technology platform enables chromatography using automated bench top platforms (for up to 12 samples in parallel) and robotic liquid handling systems (for up to 96 samples in parallel). The unique design of the PhyTip® affinity columns allows bidirectional flow of the sample through the column to maximize the use of the resi…

Previously known as SPE-DEX ® 3100

Previously known as SolventTrapOG Automated Solvent Recovery System

Previously known as SPE-DEX ® 5000

The Shamrock 163i offers the best price performance imaging and non-imaging spectrograph solutions on the market. The Shamrock 163i is offered in either an imaging version (SR-163i) or a conventional non-imaging version (SR-163), depending on your application and budget requirements. For spectroscopy applications that do not require as high a resolution or as much automation, the Shamrock 163i provides a cost-effective solutio…

Andor’s new Mechelle ME5000 Spectrograph has been designed to provide simultaneous recording of a wide wavelength range (200-975 nm) in one acquisition. It has no moving components is available in a pre-aligned detector/spectrometer format. The Andor Mechelle spectrograph is based on the echelle grating principal and its patented optical design provides extremely low cross-talk and maximum resolution compared with other spectr…

The Biotage Isolera™ LS development-scale flash purification system dramatically shortens large-scale purification run-times with flow rates of 50-500 mL/minute. Simply select or create a method, load your sample, and run – it’s that easy. New advanced features include: the ability to collect fractions on two separate wavelengths, use of up to four solvents in a single gradient and add a third isocratic co-solvent.

Previously known as DryVap ® Automated In-Line Drying and Concentration System  

Experience fast, easy to use, and superior quality pipetting in a compact system at an affordable price. Add, change, and upgrade parts and accessories as needed to accommodate changing workflows. The Microlab NIMBUS is offered in multiple platform configurations to provide the lab with a powerful and personalized solution.

Trust in the industry-leading Microlab STAR automated liquid handling platform for lasting confidence in results. The Microlab STAR can be changed or upgraded throughout its life to accommodate changing workflows, while robust and flexible programming through VENUS can accomplish any task, from simple to complex. 

Discover the ultimate in precision engineering, performance, and craftsmanship. The modular design of the Microlab VANTAGE allows the lab to optimize storage, device integration, and transport space without sacrificing deck space. As a result, rely on Hamilton to process more samples in less time without risk of error or variability.

The FastPrep-24™ 5G Instrument is quite simply the most advanced sample preparation system ever!   The only high-speed benchtop homogenizer featuring microprocessor-controlled, Hi-Def Touch Screen Programming makes the 5G the ultimate in ease, speed and performance for sample preparation applications where it is necessary to grind, lyse, or homogenize difficult and routine samples, allowing easy and reproducible isolatio…

HisTrap FF is a ready-to-use column, prepacked with precharged Ni Sepharose 6 Fast Flow for preparative purification of histidine-tagged recombinant proteins by immobilized metal ion affinity chromatography (IMAC).

HiTrap Protein A HP are prepacked columns for routine preparative purification of monoclonal and polyclonal antibodies such as human IgG.

Designed to meet the demands of modern, large-scale manufacturers Capto Q’s shorter processing times can reduce exposure of the target protein.