Drug discovery > Lead Discovery Products & Reviews

Compounds are retained on hydrophilic sorbents through polar interactions including hydrogen bonding, pi-pi or dipole-dipole interaction.  Compounds typically extracted on a hydrophilic column include analytes which have polar groups, including amines, hydroxyls and carbonyls. Elution is performed by strong polar solvents. For these types of extractions UCT offers various types of base silica, Florisil®, Alumina's, cyanopropy…

This sorbent is composed of a silica backbone bonded with a carbon chain terminated by a negatively or positively charged functional group. Ion exchange interactions occur between a sorbent that carries a charge and a compound of opposite charge. This electrostatic interaction is reversible by neutralizing the sorbent and /or analyte. Ion exchange bonds can also be disrupted by introduction of a “counter ion” to compete with…

This sorbent is composed of a silica backbone bonded with a carbon chain terminated by a negatively or positively charged functional group. Ion exchange interactions occur between a sorbent that carries a charge and a compound of opposite charge. This electrostatic interaction is reversible by neutralizing the sorbent and /or analyte. Ion exchange bonds can also be disrupted by introduction of a “counter ion” to compete with…

The same clean polypropylene tubes we use in our own column assemblies are available as an empty tube. Available in 1mL through 150mL tube sizes. The flange on the lip means the columns are suitable for use with UCT's positive pressure manifold as well as with vacuum manifold systems.

Complete Vacuum Manifold System includes a glass block, Corian® manifold lid, a cover gasket, a vacuum gauge and valve assembly, teflon tips (16 or 24), an adjustable collection rack, bulkhead luer fittings, plugs (16 or 24), and manifold safety tray.

Stainless Steel Manifold -available in single, 3 and 6 station designs. The 3 and 6 multi-station manifolds allow the simultaneous processing of multiple samples.

CLEAN SCREEN FASt THC is the newest sorbent in our FASt product lineup. It employs a process that uses positive pressure and a solid phase sorbent bed built with small pore frits to quickly and efficiently prepare urine samples for LC/MS analysis. This method eliminates timely centrifugation, reduces matrix suppression effects, and removes particulates greater than ~1μm. Samples can be diluted at a ratio as low as 1:1, which i…

The CLEAN SCREEN® THC column is copolymerized on a rigid, purified silica gel support. The two functional groups include a reverse phase, and an ion exchanger, primary amine. This column is commonly used for analyzing THC and its metabolites. It has dual functionality for acids and hydrophobic compounds.

Clean Screen® GHB is a patented mixed-mode column designed for the filtration extraction of ethylene glycol, butan diol, gamma hydroxy butyrate and butyrolactone.

Clean Screen® ETG is a proprietary carbon blend column designed for the extraction of ethyl-glucuronide from urine.  Extracts are suitable for either GC/MS or LC/MS analysis.

CLEAN SCREEN FASt EtG is the newest sorbent in our FASt product lineup. Similar to the other products in the FASt line, it employs a process that uses positive pressure and a solid phase sorbent bed built with small pore frits to quickly and efficiently prepare urine samples for LC/MS analysis. This filtration device helps to combat the significant ion suppression EtG/EtS urine analysis typically suffers from using a standa…

Enviro-Clean 500mg/6mL cartridge HLDVB w/Polyethylene frits. UCT's new polymeric highly cross-linked DVB bead. It is used with EPA Methods  528, 529, 537, 553, 8141B and 8330.

Kit geared towards EPA Method 8270-Extraction of Acids, Neutrals, and Bases in 500 mL Water. Kit includes: 30 x 8270 Extraction Cartridges; 30 x Carbon Extraction Cartridges; 30 x Cartridge Adaptors; 12 x Large Volume Transfer Tubes.

UCT is excited to introduce our small and large push-thru glyphosate purification cartridges. Simply pass your aqueous extracts through either the small or large filter cartridge format to effectively remove all organic material and surfactants that hinder the chromatographic analysis of both glyphosate and glufosinate.

UCT's Enviro-Clean® Polymeric WAX Cartridges w/Polyethylene frits have been successfully utilized for the extraction of 26 diverse per- and polyfluoroalkyl substances (PFASs) in drinking water in addition to the 14 covered in the US EPA Method 537.  

Designed to retain excess organometallic catalysts commonly utilized in industrial synthesis enabling purification by simple filtration. 

Simple and Accurate Fractionation for EPH Testing with New Silver Functionalized Enviro-Clean Fusion®Ag+ This novel sorbent is designed to help overcome the challenges associated with traditional silica gel fractionation. Featuring silver ions anchored onto a solid support, this chemistry provides enhanced selectivity, capacity, and overall performance.

UCT's Enviro-Clean® Polymeric WAX Cartridges w/Polyethylene frits have been successfully utilized for the extraction of 26 diverse per- and polyfluoroalkyl substances (PFASs) in drinking water in addition to the 14 covered in the US EPA Method 537.  

SIGIS 2 is a scanning imaging remote sensing system that allows rapid identification, quantification and visualization of gas clouds from long distances.   The system maps a predefined area and results of the analysis are visualized by a video image, overlaid by a chemical image. The SIGIS 2 is part of the equipment of emergency response forces around the world. In addition, SIGIS systems are applied in environmental app…

The EM 27 is a ruggedized remote sensing system providing high performance spectroscopy in the field. The EM 27 can easily be deployed in the field for various air monitoring applications.Emissions from smoke stacks, waste disposal and hazardous emissions from chemical accidents can be observed with an operating range of typically several kilometers. The EM 27 SUN features a solar tracker for measurements of atmospheric…

The CONFOCHECK is a dedicated FTIR system for the investigation of proteins in water. Its specific configuration facilitates a fast data acquisition (ca. 30 sec. per sample) with a high sample throughput controlled by an extremely user friendly software interface. Main applications for the CONFOCHECK are the detection and quantification of conformational changes in proteins and the protein concentration determination. Quant…

The PMA 50 module has been dedicated developed for Polarization Modulation measurements.   Both linear dichroitic measurement techniques like PM-IRRAS and circular dichroitic experiments like VCD spectroscopy can be realized using this accessory. It can be adapted to Bruker TENSOR and VERTEX FTIR spectrometers. All optic and electronic components in the PMA 50 module are optimized for the Polarization Modulation. Both…

CryoSAS is an automated high sensitivity FT-IR system for the quality control of solar and electronic grade Silicon according to international ASTM/SEMI standards.   Although sample cooling to very low temperatures is required, CryoSAS operates without cryogenic liquids, is easy to use and optimized for the requirements of industry customers. CryoSAS combines Bruker's high performance FT-IR spectrometers with bui…

Thermogravimetric analysis (TG) follows changes in mass of the sample as a function of temperature yielding information of the various component amounts. Whereby identification of gases released during thermal treatment cannot be performed just by thermal analysis. Fourier-Transform-Infrared (FTIR) spectroscopy overs an excellent solution for the identification of unknown compounds. IR, a classical technique, depends upon t…

Bruker’s microplate extension HTS-XT allows the application of FTIR spectroscopy as method for high-throughput screening. This external module can be connected to different Bruker Optics FTIR spectrometers. Depending on its configuration it can be used for measurements in the mid infrared to the near infrared and even the VIS range. The sampling plates for the IR analysis correspond to the standardized 96- or 384-well mi…