Life Sciences Products & Reviews

Isolate High-Molecular-Weight DNA for Long-Read-Sequencing applications.

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay provides a no-wash, one-step Annexin V assay that allows continual monitoring of cell state to determine apoptotic onset using a plate-reading luminometer.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

The Caspase-Glo ® 1 Inflammasome Assay  directly measures inflammasome activation with a simple add-mix-measure protocol.

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruntion by components of the cell-mediated.

The TNT® Coupled Reticulocyte Lysate Systems offer researchers an alternative for eukaryotic cell-free protein expression: a single-tube, coupled transcription/translation system. The TNT® Lysate Systems greatly simplify the process and reduce the time required to obtain in vitro translation results.

Wizard® Plus Megapreps DNA Purification System provides a simple and rapid method for large-scale purifications of plasmid DNA that eliminates the need for cesium chloride:ethidium bromide gradient centrifugation. Use of this system requires only a centrifuge, a vacuum source and a vacuum manifold. The system yields greater than one milligram of high-copy-number plasmid DNA (200–20,000bp) from a 1,000ml culture in less than th…

ProteaseMax™ Surfactant is a high-quality reagent for use in protein and peptide sample preparation.   ProteaseMax™ Surfactant solubilizes proteins and ensures fast and improved protein digestion with trypsin or chymotrypsin. It is designed to degrade over the course of a digestion reaction, yielding products that are compatible with downstream methods such as mass spectrometry (MS) and liquid chromatography (LC). For…

HaloLink - Promega Magnetic Beads for Covalent immobilization of HaloTag® fusion proteins.   Features of the Promega HaloLink Magnetic Beads: • Magnetic-Based: Easy and quick immobilization of HaloTag® fusion proteins with minimal loss of sample material. • Covalent Bond: Allows stringent washing of immobilized HaloTag® fusion protein, removing nonspecific proteins and enhancing overall data.  • Multiple Appli…

Developing a precise, accurate, and reliable assay is never easy. From raw material sourcing, to technical considerations, to optimization and ultimate scale-up, a development team counters challenges that strain resources and delay timetables. Savvy developers recognize that assay development and optimization move smoother when optimal raw materials and expert support are identified early in the process.

Predesigned probe assays for gene expression analysis

Custom adapters for multiplex next-generation sequencing

Predesigned primers for gene expression analysis

Specialized purification to ensure high performance

Larger quantities for in vivo, high throughput and commercial projects  

For Mpox qPCR assay development

If you commercialize Molecular Diagnostics (MDx), create Laboratory Developed Tests (LDTs), or conduct preclinical research, then your final kit, assay, or modality must have an extraordinary level of quality to comply with strict regulatory or study standards. In the case of oligonucleotide raw materials available with custom specifications, the only option you should consider is Custom cGMP Oligos.

Modulation of gene expression with modified oligos

Proteinase K from Tritirachium album ELEVATE  

Proteinase K from Tritirachium album ELEVATE

Run at Higher Flow Rates and Lower Backpressures without Sacrificing Resolution

Bringing You Closer to Universal DetectionWhen carrying out chromatographic runs, do you require any of the following? •Need confidence that you have seen all the peaks in your separation •Require unattended, reproducible operation •Collect fractions that do not have chromophores for UV/Vis triggering With Waters new 2420 ELSD, you’ll get the answers you’re looking for faster. And, the Waters 2420 ELSD is the smallest ELSD on…

eXtended Performance [XP] 2.5 µm Columns are high efficiency, low backpressure HPLC columns that can be easily utilized across all HPLC, UHPLC and UPLC Technology platforms. Low Backpressure. High Throughput. Improved Productivity. • 40% lower backpressure than sub-2-µm UPLC columns • Increase flow rate to increase throughput • Equivalent backpressure and superior performance to core-shell columns • Improve HPLC productivity 2…

The 1.7 µm Ethylene Bridged Hybrid [BEH] particle is one of the key enablers behind UPLC® technology.It is available in three different pore sizes [130Å, 200Å and 300Å] and several bonded phases for reversed-phase and hydrophilic interaction chromatography and is applicable from small molecule to large biopharmaceutical analysis. Due to the intrinsic chemical stability of hybrid particle technology, a wider usable pH range [pH…