Drug discovery > Pre-Clinical Development Products & Reviews

BlueScreen HC uses a single cell strain, which permits 8 compounds to be tested across 8 dilutions (2-fold serial), together with untreated and positive controls, in one 96-well microplate. After arraying test compounds and dilutions, growing cells are added to each well. For studies without S9 metabolic activation data are collected after incubation (48h) using a multimode microplate reader. For studies incorporating S9 metab…

The cost of drug discovery continues to rise while the output of new NDAs continues to fall. Consequently it has never been more important to address attrition rates in drug discovery and development. Early indication of toxicity in a molecule or lead family means that discovery resources can be directed either at other chemical series if these are available or towards ‘breeding’ out undesirable properties. Gentronix and Apred…

FasL-Strep, a stable homotrimer, efficiently induces the CD95 pathway of apoptosis and is highly suited for evaluation of CD95 (Fas) receptor-ligand interaction. Human or murine FasL-Strep (CD95L-T4) is an engineered human or murine Fas (CD95) ligand. C-terminal fusion of the T4-FOLDON to the extracellular FasL (CD95L) receptor-binding domain (E142-L281) results in bioactive, conformationally stabilized, well defined trimers…

Small and efficient

Fast comminution down to 10 µm

The universal grinder for every application

Everything you need for sieving

The most precise way of sample division

SigmaScan - Analyze Images Automatically An image analysis package for scientists, engineers and technicians that provides an easy method to measure virtually any object that can be photographed or scanned. Manipulate images in a wide variety of ways for your professional needs. Convert images to different types, paste or splice images from one type to another, or modify pixel resolution while maintaining the aspect ratio of…

TableCurve 2D - Curve Fitting Made Fast and Easy A linear and non-linear curve fitting software package for engineers and scientists that automates the curve fitting process and in a single processing step that instantly fits and ranks over 3,600 built-in frequently encountered equations enabling users to easily find the ideal model to their 2D data within seconds.TableCurve 2D’s state-of-the-art data fitting includes capabil…

TableCurve 3D - Model Complex Data Sets Fast and Easy A linear and non-linear surface fitting software package for engineers and scientists that automates the surface fitting process and in a single processing step, instantly fits and ranks about 36,000 out of over 450 million built-in frequently encountered equations enabling users to find the ideal model to their 3D data within seconds. TableCurve 3D’s built-in equation se…

Find the most obscure patterns and separate overlapping peaks by statistically fitting numerous peak functions to one data set. The background can be fit as a separate polynomial, exponential, logarithmic, hyperbolic or power model. PeakFit uses three procedures to automatically place hidden peaks; while each is a strong solution, one method may work better with some data sets than the others. • The Residuals procedure initia…

The first program that completely automates the process of analyzing signals. Save precious time by eliminating the programming time normally required for performing sophisticated signal analysis. Key features of AutoSignal™ include:• Perform complex signal analysis with a mouse click - no programming required• Quickly locate your signal components• Precisely estimate with advanced parametric modeling• Graphically review sign…

The CYTOOchamber™ is a 35mm footprint device specially designed and manufactured for the 2x2cm² square CYTOOchip™ format which enables you to do high resolution timelapse microscopy. The CYTOOchamber uses a patented magnetic system for easy assembly. The CYTOOchamber has the same footprint as standard 35mm culture dishes and therefore will fit into all 35mm microscope stage adaptors. Components: • 1 bottom plate • 1 upper mai…

SCOPE OF APPLICATION ASEPTIC FILLING • Pharmaceutical • Diagnostic • Biopharmaceutical • Disposable filling • Aseptic liquid filling • Peristaltic liquid filling • No cleaning validation • Easy product change-over • Ideal for small batch production • No cross contamination • High accuracy filling VERY COMPACT Machine dimensions are 1.13 x 2.05 m, i.e. FMB210 takes up very little space in a cleanroom. SHORT CHANGE OVER TIME Ide…

The MS-3 laser scanner offers the fastest read performance in embedded compact bar code scanners. The wide scan angle of 70 degrees is coupled with ultra-compact size and flexible mounting. • Decodes/second: up to 1000 • Read Range: 2 to 10” (51 to 254 mm) • Wide Scan Angle • IP54 Enclosure High performance and flexibility make the MS-3 the optimal choice for reliable reading in embedded instruments. Compact & Lightweight: The…

Cell biology is reliant on the investigation of unmanipulated naturally occurring cells. State-of-the-art receptor specific isolation procedures, however, leave binding reagents on the isolated cells which is likely to induce unwanted cell modifying signalling events. This can now be prevented by using a novel purification approach called Streptamer® technology. Mild purification conditions at low temperatures along with a q…

The NorDiag Bullet instrument is CE IVD ready and provides TRUE walk away automated sample preparation for molecular diagnostics. The NorDiag Bullet is compact yet flexible, designed to provied targetend solutions for the user's needs.

The BioSorter is a large particle flow cytometer designed to analyze, sort and dispense biological materials and other objects ranging in size from 10 to 1500 microns in diameter. The system is designed to handle objects which are too large or too fragile for traditional flow cytometers. Examples include small multicellular model organisms, delicate large cells / cell clusters, small seeds and beads used as microcarriers or fo…

StatSoft's flagship product line is the STATISTICA suite of analytics software products. STATISTICA provides the most comprehensive array of data analysis, data management, data visualization and data mining procedures. Its techniques include the widest selection of predictive modeling, clustering, classification and exploratory techniques in one software platform. STATISTICA analytic capabilities are complemented by a host of…

Universal Caps - Seal multiple size tubes with one size cap. Easy to use, polyethylene caps feature a universal fit. Seal caps with one handed use. Caps provide tight, leak-proof seal for standard glass or plastic tubes. The innovative design of the Heathrow Scientific Universal Caps fit larger tube sizes inverted and smaller tube sizes upright. Compatible with tube sizes 10 mm, 12/13 mm or 16 mm. Available in Blue, Green, Red…

10, 20- and 30-Place Cardboard Slide Tray - Features thumb cut for easy slide removal Heathrow Scientific cardboard slide trays hold standard slides (75 x 25 mm and 3 x 1"). The horizontal compartments are recessed to protect the specimens when the cover is closed. Features thumb cut for easy slide removal. Now available with blue and green tape and imprinting.

20-Place Slide Tray Racks - Store multiple trays for easy retrieval Heathrow Scientific 20-Place Slide Tray Racks are ideal for Microbiology, Histology, and Pathology fields. Sturdy ABS rack holds five of the 20-place slide trays. Eliminates the worry of breakage during retrieval—easy access to each of the trays. Matching clasps provide area for identification labels and doubles as a handle. Label or write with permanent pen o…

15-, 40-, and 78-Capacity Slide Holders 15-, 40-, and 78-Capacity Slide Holders from Heathrow Scientific hold slides during evacuation, cleaning, and drying. Cut from chemical-resistant polyethylene. Solid and strong with rubber feet for benchtop stability.