Drug discovery > Pre-Clinical Development Products & Reviews
Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.
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ImmPRESS™ POLYMER REAGENTS
Vector Laboratories Inc.The highly sensitive, one-step, ready-to-use ImmPRESS™ Polymer Detection reagents are the result of novel conjugation methods and micropolymer chemistry developed at Vector Laboratories.
MOUSE ON MOUSE (M.O.M) IMMUNODETECTION KITS
Vector Laboratories Inc.The Vector® M.O.M.™ Kits are specifically designed to significantly reduce endogenous mouse Ig staining when using mouse primary antibodies on mouse tissue.
ENZYME SUBSTRATES
Vector Laboratories Inc.Along with the traditional chromogenic substrates, Vector Laboratories also offers a wide variety of proprietary enzyme substrates.
ImmEdge Hydrophobic Barrier Pen
Vector Laboratories Inc.The ImmEdge™ Pen (H-4000) is an improvement over the PAP pen for immunohistochemistry, immunocytochemistry, immunofluorescence, and in situ hybridization.
VECTASHIELD MOUNTING MEDIA
Vector Laboratories Inc.VECTASHIELD® Antifade Mounting Medium is a unique, stable formula for preserving fluorescence. VECTASHIELD® Mounting Medium prevents rapid photobleaching of fluorescent proteins and fluorescent dyes.
Quant*Tag Biotin Quantitation Kit
Vector Laboratories Inc.The Quant*Tag™ Biotin Kit (BDK-2000) is designed to determine the amount of free biotin in solution or the number of biotins attached to nucleic acids, proteins, or other macromolecules. This kit can be used to determine accurately the labeling efficiency of biotin-labeled molecules.
BIOTINYLATED SECONDARY ANTIBODIES
Vector Laboratories Inc.Vector Laboratories’ affinity-purified antibodies are of unmatched quality. These antibodies are prepared using proprietary immunization schedules that produce high affinity antibodies. The antibodies are then purified by affinity chromatography, and cross-reactivities that are likely to interfere with specific labeling are removed by solid phase adsorption techniques.
FLUORESCENT SECONDARY ANTIBODIES
Vector Laboratories Inc.Vector Laboratories' fluorescent secondary antibodies are unmatched in quality for immunological techniques. All antibodies are prepared using proprietary immunization schedules that produce high affinity antibodies.
Global DNA Methylation Assay–LINE-1
Active MotifELISA-based assay for the detection and quantification of global DNA methylation in human genomic DNA
TransAM® NFκB Transcription Factor Binding Assays, Family Kit
Active MotifSimple plate-based non-radioactive DNA-binding assays that facilitate the study of NFkB transcription factor activation in mammalian tissue and cell extracts
TransAM® Nrf2 Transcription Factor Binding Assay
Active MotifSimple solution for studying Nrf2 activation in human, mouse and rat model systems
DNMT Activity / Inhibition Assay
Active MotifHighly sensitive and rapid microplate-based assay to simplify the measurement of DNA methyltransferase activity
Global 5-hmC Quantification Kit
Active MotifELISA-based assay designed to detect and quantify 5-hydroxymethylcytosine (5-hmC) levels in genomic DNA from different sample types
Histone H3 PTM Multiplex Assay
Active MotifMultiplex epigenetic assay for high throughput profiling of histone post-translational modifications
Total Histone H3 ELISA
Active MotifSimple, sensitive method for detecting changes in histone methylation levels from purified core histones or histones isolated by acid extraction
Antibodies and Immunohistochemistry Reagents
Alpha Laboratories LtdAn extensive range of antibodies from BioPorto and Wako suitable for use in various immunoassay techniques including: ELISA, Western Blotting, Immunohistochemistry and Immunoprecipitation. Products Include: Variability Free IgE Immunohistochemistry stains and reagents Recombinant Proteins Primary Antibodies Secondary Antibodies
Viresolve® Pro Shield H Prefilters
Merck KGaA, Darmstadt, GermanyFor removal of parvoviruses from therapeutic protein feed streams
Mobile HomeCage™
NeurotarCutting edge brain research in awake mice without the biases introduced by anesthetics.
Tedlar® Gas Sampling Bags
Sigma-Aldrich SupelcoTedlar® gas sampling bags are recommended in many US EPA methods including TCLP and methods TO-3 (VOCs), TO-12 (NMOC), TO-14A (VOCs), TO-15 (VOCs), ASTM D-5504 (reduced sulfur compounds) and a variety of atmospheric gas methods. Tedlar® bags are an excellent value and offer several features over competitor versions. Benefits: Unique valve and seam-sealing process ensure bags are sturdy and leak-proof under the mo…
ToxiLight® Non-Destructive Cytotoxicity BioAssay Kit
Cambrex Bioproducts EuropeThe ToxiLight® BioAssay Kit is a bioluminescent, non-destructive cytolysis assay kit designed to measure the release of the enzyme, adenylate kinase (AK), from damaged cells. The ToxiLight BioAssay Kit also facilitates high content screening by allowing other tests to be performed on the original cells For example, the ToxiLight BioAssay Kit is fully compatible with the ReportaLight™ BioAssay Kit, thus facilitating measurement…
PULVERISETTE 5 classic line PLANETARY BALL MILL
Fritsch GmbH - Milling and SizingFast, contamination free grinding below 1 micron. Handles sample volumes from 1 ml up to 4 x 225 ml.
VARIO-PLANETARY MILL PULVERISETTE 4
Fritsch GmbH - Milling and SizingIn contrast to conventional Planetary Mills, the rotational speed of the grinding bowls and supporting disk can be configured separately in the Vario-Planetary Mill PULVERISETTE 4 classic line with 2 working stations. Your advantage: A single mill for mechanical activating and alloying providing optimum grinding conditions suited to the respective material to be ground and the size of the grinding bowls and balls! For resul…