Separations Products & Reviews

Size-based separations of peptides, proteins, and viral vectors

With integrated chemistry, software and instrumentation protocols, Benchtop Systems provide research and development teams in the pharmaceutical, chemical and consumer products industries with standard configurations and applications designed to accelerate R&D while reducing costs. The Benchtop System won the 2007 ALA New Product Award Designation at LabAutomation2007! Symyx Benchtop Systems applications currently available in…

XBridge® and ACQUITY UPLC® Oligonucleotide C18 Columns for Synthetic Oligonucleotide Analysis and PurificationIon-pair, reversed-phase separation of detritylated oligonucleotides on sub-3 micron particles yields exceptional component resolution.UPLC ® technology increases sample throughput while maintaining necessary oligonucleotide component resolution.LC/UV and LC/MS methods for enhanced quantitative and qualitative oligonuc…

Spark Holland has been operating at the forefront of autosampler design for 25 years. Spark’s Reliance™ autosampler is the first true bio-injector, and is preferred by customers for 4 simple reasons: -   Lowest possible carry-over-   High-speed wash cycles-   Low maintenance-   Conditioned sample storage The Reliance™ autosampler complies with GLP requirements and can be coupled with most LC-MS systems. It runs fully integra…

Hypersil Green columns allows for sharp, symmetrical and easily quantifiable assays to be developed quickly and easily. Product detail: Hypersil Green columns are developed for environmental analysis. The chromatographic separation of phenols, nitrophenols, chlorophenols, triazines, urea pesticides, phthalates and many other polar compounds requires a separating phase specially designed for the task. Hypersil Green ENV has…

Thermo Electron Corporation offers a full range of extraction accessories to complement both traditional column and 96-well plate technologies. These include vacuum manifolds, collection tubes and plates and method development kits.

o   The benchmark in based deactivated silica columnso   Sharp peaks and improved symmetry for basic compoundso   Value and performance from a globally referenced column Product detail: DASH columns are packed to the same high standards as our analytical columns, and offer superioir chromatographic resolution in a design that eliminates the need for endfittings and wrenches during column change over. This makes column inst…

Fluophase RP Columns o   A range of perfluorinated phases for alternative selectivityo   Extra retention and selectivity for halogenated compoundso   Select from 100Å and 300Å pore sizes Product detail:For alternative selectivity to traditional alkyl phases, we recommend you try the perfluorinated phases of Fluophase columns. The stationary phase of Fluophase RP contains a perfluorinated C6 chain, where every hydrogen atom on…

Hypersil 100 C8 Columns Compared to other classical materials, Hypersil 100 has a smaller pore diameter of only 100Å, which creates a higher specific surface area that can be advantageous where longer retention times are needed, such as chromatography of polar compounds. Product detail: Compared to other classical materials, Hypersil 100 has a smaller pore diameter of only 100Å, which creates a higher specific surface area…

The UNIGUARD drop-in cartridge fits both our guard systems: the stand alone UNIGUARD and the Direct Connection UNIGUARD. Product detail: We recommend all analytical columns are protected by a guard cartridge, which is replaced on a regular basis. The ID of the analytical column determines the correct ID for the guard cartridge. We offer 10x1.0, 10x2.1, 10x3.0, 10x4.0 (for use with both 4.0 and 4.6mm ID analytical columns) i…

RP-HPLC for Protein/Peptide Analysis and PurificationJupiter® HPLC columns offer optimized reversed phase solutions for protein and peptide characterization and purification. A wide variety of phases (C18, C12, C5, C4) and dimensions (capillary-preparative)/bulk media are available to support the majority of separation requirements.Jupiter 300 - 300 Å columns designed to purify intact proteinsJuptier Proteo - 90 Å columns eng…

Better digestions for better analyses.

Market Leading LC-TOF-MS with Unrivalled Sensitivity, Exact Mass and Dynamic Range for Qualitative Applications The Waters LCT Premier™ XE is the market-leading orthogonal acceleration time-of-flight (oa-TOF) benchtop mass spectrometer for LC applications. Based on proven and reliable technology, the LCT Premier XE provides unrivalled all round performance for those challenging LC/MS applications. The LCT Premier XE's high sen…

Increase the throughput of your pyrolysis laboratory by using the AS5250 Pyroprobe® Autosampler. The AS5250 provides hands-free analysis of up to 36 samples and enhances operational capacity allowing unattended operation over a weekend or holiday period. Solid, viscous liquid and powder samples are analyzed directly, eliminating the need to perform lengthy sample extractions or derivatizations. A patented heating method provid…

Setting the Standard for pH Method DevelopmentRugged reversed phase HPLC columns that offer extended lifetime under extreme pH conditions and excellent stability for reproducible, high efficiency separations. Take full advantage of high and low pH conditions (pH 1-12) to manipulate selectivity Expect longer column lifetime with patented TWIN-NX™ technology Ideal for analytical and preparative separations of basic and acid…

Waters ACQUITY UPLC - Dramatic Improvements in Speed, Sensitivity and Resolution Whether you work in methods development or quality assurance, in drug discovery and development or testing for safety in food supplies, you seek a productivity edge. With the ACQUITY UPLC® System, now you can get more information in a single, short run than you've ever seen with HPLC. Waters ACQUITY UPLC System UltraPerformance LC® (UPLC®) techn…

Excellent low pH stability and high mass loading capability

XBridge Columns include a selection of 10 general-purpose and application-specific sorbents that cover a wide range of particles sizes for analytical and preparative HPLC applications.   XBridge Column users can quickly develop robust methods using mobile phases throughout the entire pH range of 1-12. XBridge OBD™ Preparative Column users, benefit from high pH and temperature stability to provide increased mass loading f…

The new Finnigan LCQ Advantage MAX delivers high productivity LC/MS/MS analysis in a routine HPLC environment. Product detail: The Finnigan LCQ Advantage is the workhorse ion trap mass spectrometer for high productivity LC/MS/MS results and is easily upgraded to MSn performance. The Finnigan LCQ Advantage MAX now features the universal Ion Max source that allows simple tool-less switching of ionization probes. Ion Sweep Gas…

VanGuard Pre-Columns for UPLC® separations are guard columns that are designed for use with the ACQUITY UPLC® system. These guard columns use an ultra-low volume design (patent pending) that efficiently protects UPLC column performance. This ultra-low volume design does not compromise the UPLC holistic design approach to higher efficiency, greater resolution and increased throughput. Guard columns are typically used in appli…

The Sirocco™ plates are the most technologically advanced protein precipitation plates in the market and enable high-throughput “in-well” protein precipitation of biological samples without the fear of cloudy filtrates or clogged devices. It also provides optimum performance in faster processing time by reducing steps in ‘in-well’ sample processing and complete recovery of clean filtrate from smaller plasma sample volumes.

Designed specifically for polymer characterization, the Styragel® columns are grouped into the HR series for low-to-mid molecular weight samples, the HT series for high-temperature applications, and the HMW series for high molecular weight samples. Specifically controlled styrene divinylbenzene formulations provide reproducible performance in your GPC applications.

Packed with hydroxylated polymethacrylate-based gel, Waters Ultrahydrogel™ SEC columns are ideal for the analysis of aqueous-soluble samples, such as oligomers; oligosaccharides; polysaccharides; and cationic, anionic, and amphoteric polymers. Measuring 7.8 mm x 300 mm, these high-resolution columns offer many advantages over conventional aqueous SEC columns, such as: - A wide pH range (2–12) - Compatibility with high concen…

Sep-Pak Plates enable high throughput solid-phase extraction with the same silica sorbents that have been proven for years in Sep-Pak Cartridges. The plate design has been optimized for automated sample handling systems as well as for standard vacuum manifolds. Sep-Pak Plates are available with different silica sorbent mass selections to optimize sample loading.

The SPECTRUM range of High Performance CCC (HPCCC) equipment is based on traditional liquid/liquid partitioning and extends the purification options available to chemists, in Discovery and Development, who are looking purify samples from mgs to 5-10 grams of material. The equipment is easily connected and interfaced into existing LC equipment and provides options when existing solid phase technology cannot obtain the resolutio…