Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Biotinylated Human TNF-alpha Protein, His,Avitag™, active trimer (MALS verified)

ACROBiosystems

Biotinylated Human TNF-alpha, His, Avitag (TNA-H82E3) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™), and has a calculated MW of 20.0 kDa. The protein migrates as 21 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

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Human VEGF165 Protein, His Tag

ACROBiosystems

Human VEGF165, His Tag (VE5-H5248) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the N-terminus, and has a calculated MW of 21.1 kDa. The protein migrates as 27-28 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

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Biotinylated Human VEGF165 Protein, His,Avitag™

ACROBiosystems

Biotinylated Human VEGF165, His,Avitag(VE5-H82Q0) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™), and has a calculated MW of 22.4 kDa (monomer). The protein migrates as 25-33 kDa (monomer) under reducing (R) condition, and 42-55 kDa (homodimer) under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

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Metabolomic Products

Cambridge Isotope Laboratories

An innovative technology termed isotopic ratio outlier analysis (IROA) was developed to overcome the analytical challenges associated with current, stable isotope labeled compounds used in untargeted /targeted metabolic profiling.   These challenges minimally pertain to analytical variance, artifactual peaks, and metabolite identification. The IROA method uses metabolic incorporation of heavy (95% 13C) and light (5%…

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Standards for Environmental, Food, Water, and Human Exposure Analysis

Cambridge Isotope Laboratories

 As new technologies and applications to study environmental, food, water, and exposure contaminants advance, CIL continues to maintain a leadership role working with researchers to develop new standards to meet the latest needs. With new instrumentation and extraction procedures allowing detection limits approaching attogram levels in some cases, the need for highly accurate isotope standards has never been greater.    

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Metabolomic Mixes and Kits

Cambridge Isotope Laboratories

CIL offers a variety of metabolomic mixes and kits that are designed to aid ease of use in untargeted or targeted metabolomics (for quality control, qualification, and/or quantitation). The mixtures are offered neat or as solutions, while the kits are additionally supplied with a user manual. CIL can also provide customized mixes tailored to your specific needs.

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