Drug discovery > Target Discovery Products & Reviews

Promega has partnered with ATCC to offer unparalleled STR testing service for human cell line authentication.   This service provides easy access to proven and comprehensive validation techniques. Promega's proprietary PowerPlex® and GenePrint® STR technology coupled with ATCC's considerable experience profiling human cell lines and extensive internal assets around STR profiling data interpretation is particularly r…

QuantiFluor® ONE system maximizes sensitivity and efficiency for dsDNA quantitation.   The QuantiFluor® ONE dsDNA System contains a fluorescent double-stranded DNA-binding dye (504nmEx/531nmEm) developed for use in an “add-and-read” format for dye and standard, making sample quantitation easy. This system enables sensitive quantitation of small amounts of double-stranded DNA (dsDNA). The QuantiFluor® ONE dsDNA Sy…

The Maxwell® Clinical Sample Concentrator (CSC) automated nucleic acid extraction system is designed for clinical laboratories needing to process multiple samples for critical downstream assays. This easy-to-use, cGMP-compliant system provides consistent, high-quality results with every run, allowing you to manage your workflow and gain efficiency. The purification methods use sample lysis and binding to paramagnetic par…

The QuantiFluor® ONE dsDNA Dye is a fluorescent double-stranded DNA-binding dye (504nmEx/531nmEm) prepared for an “add-and-read” format making sample quantitation easy. This dye enables sensitive quantitation of small amounts of double-stranded DNA (dsDNA).   The QuantiFluor® ONE dsDNA Dye is intended for use as a general purpose reagent in the US and is suitable for use by clinical laboratories as a component of la…

New line of standard and low-profile PCR plates for improved PCR efficiency.   Improve PCR efficiency with a new line of PCR plates manufactured with the best raw materials using the latest in production technologies. Standard and low profile PCR plates in clear and white are suitable for use in most thermal cyclers. These new plates combine extra-thin and uniform wall thickness with a rigid upper PP deck for easy handli…

All BRAND PCR products are available in white plastic, uniformly colored with titanium dioxide (TiO2) for optimal results when performing quantitative PCR (gPCR) with fluorescent signals.   BRAND microcentrifuge tubes fit most common rotors and may be spun up to 20,000 RCF (10,000 RCF for 0.5mL). Manufactured from virgin polypropylene, these highly translucent tubes are free from flash, air bubbles, and streaks. Caps are…

BRANDplates® inertGrade™ 96-well plates are especially suited for cell culture applications when adhesion is not desired. These plates are specifically designed for the cultivation of suspension, tumor, and stem cells, as well as other spheroid or 3-dimensional tissue culture models. They feature a surface that reduces cell adhesion and protein absorption to minimize enzyme and cellular activation. All BRANDplates® inertGra…

Innovative cell culture plates and inserts for co-culture, migration/invasion assays, 3D tissue preparation and more.   The BRANDplates Insert System, co-developed with the Fraunhofer Society, offers an innovative expansion of the BRAND cell culture product line. The new Insert system consists of 24-well standard and 6-well specialized plates and strips of hanging cell culture inserts for applications such as co-culture,…

Adaptable Microplate Solution for Custom ELISA Applications. BRANDplates® Strip Plates are especially suited for laboratories designing custom ELISA applications, or desiring increased flexibility in their ELISA application. To ensure the effective binding of a wide range of antigens or antibodies to the microplate surface, the strip plates are available in two treatment types: pureGrade™ or immunoGrade™. The pureGrade™ plate…

The BRAND Liquid Handling Station pipetting robot handles routine tasks at high speed and with the highest precision. The LHS closes the gap between electronic pipettes and highly complex, expensive pipetting robots. It is a quiet and compact instrument with a unique front door allowing it be set up in tight quarters. The instrument has 7 working positions and 5 available liquid ends with single channel volumes up to 1000uL an…

The Glucose-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of glucose in biological samples.

The Glutamate-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of glutamate in biological samples.

The Glutamine/Glutamate-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of glutamine and glutamate in biological samples.

The Succinate-Glo™ JmjC Demethylase/Hydroxylase Assay is a bioluminescent assay for detecting the activity of JumonjiC (JmjC) histone demethylases and many Fe(II)/α-ketoglutarate-dependent dioxygenases that use α-ketoglutarate as substrate and release succinate as a product.

Count on minimal interference from test compounds when screening your compound library using luminescent, ATP-based kinase assays. We offer the ADP-Glo™ Kinase Assay, Kinase Selectivity Profiling Systems and hundreds of Kinase Enzyme Systems. These sensitive, reliable assays are easily scaled to meet your throughput needs and can be used with virtually any kinase and kinase substrate combination.

Automated Purification of High-Quality Total RNA with an Enhanced miRNA Enrichment

Sensitive Quantitation of Single-Stranded DNARequires less DNA than spectrophotometry

Directly Measure HDAC-Test Compound Affinity and Residence Time in Live Cells

BRET-Based Assays to Detect Protein:Protein Interactions in Live Cells

The BRAND Liquid Handling Station (LHS) pipetting robot handles routine tasks at high speed and with the highest precision.

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay provides a no-wash, one-step Annexin V assay that allows continual monitoring of cell state to determine apoptotic onset using a plate-reading luminometer.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

The Caspase-Glo ® 1 Inflammasome Assay  directly measures inflammasome activation with a simple add-mix-measure protocol.

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruntion by components of the cell-mediated.