Drug discovery > Target Discovery Products & Reviews

Designed to identify the physical interactions of a miRNA with endogenous mRNA transcripts

Simple plate-based non-radioactive DNA-binding assays that facilitate the study of NFkB transcription factor activation in mammalian tissue and cell extracts

Complete solution for convenient, accurate monitoring of protein/DNA interactions

Simple solution for studying Nrf2 activation in human, mouse and rat model systems

An optimized and streamlined protocol for high-resolution genome-wide mapping of transcription factor binding sites in the human and mouse genomes

Providing the highest quality ChIP-enriched DNA for analysis by qPCR or Next Generation sequencing

Specially formulated to perform ChIP from PBMCs, including lymphocytes (T cells, B cells and NK cells), monocytes and dendritic cells

Modified ChIP assay that utilizes the CRISPR/Cas9 system to target a specific DNA locus for immunoprecipitation

Perform ChIP without the need for protein-specific antibodies

Highly sensitive and rapid microplate-based assay to simplify the measurement of DNA methyltransferase activity

ELISA-based assay designed to detect and quantify 5-hydroxymethylcytosine (5-hmC) levels in genomic DNA from different sample types

Multiplex epigenetic assay for high throughput profiling of histone post-translational modifications

Asensitive, high-throughput method for quantifying global changes in the level of specific histone modifications

Asensitive, high-throughput method for quantifying global changes in the level of specific histone modifications

Purification of core histones (H2A, H2B, H3 and H4) using very small amounts (as little as 0.9 x 105 cells) of starting material

Simple, sensitive method for detecting changes in histone methylation levels from purified core histones or histones isolated by acid extraction

Detect and capture DNA fragments containing 5-hydroxymethylcytosine (5-hmC) DNA methylation for analysis

Immunoprecipitate and enrich for DNA fragments containing 5-hydroxymethylcytosine (5-hmC)

Immunoprecipitate and enrich for single-stranded DNA fragments containing 5-methylcytosine (5-mC)

Fast magnetic assay capable of efficiently isolating methylated CpG islands from fragmented genomic DNA

Novel technology that allows for positive identification of unmethylated DNA fragments

Reagents to measure luciferase reporter signal as part of the LightSwitch Luciferase Assay System

Single base-pair, high-throughput solution for analysis of methylated DNA regions

Comprehensive services for DNA enrichment and profiling of genomic regions marked by DNA methylation or DNA methyl variants

Fastest, most efficient methylated DNA enrichment method on the market