Drug discovery > Target Discovery Products & Reviews

Hedgehog pathway inhibitor; Inhibits Smoothened (SMO)

Activin/NODAL/TGF-ß pathway inhibitor; Inhibits CK1, ALK5 and p38 MAPK

MEK/ERK pathway inhibitor; Inhibits B­RAF V600E

Notch pathway inhibitor; Inhibits ?-secretase

Tyrosine kinase inhibitor; Inhibits ABL, SRC, LCK and YES

Notch pathway inhibitor; Inhibits ?-secretase

Inhibits EGFR and VEGFR

Glucocorticoid pathway activator; Activates glucocorticoid receptor

cAMP pathway activator; Activates cAMP-dependent protein kinases

Immunomagnetic positive selection cell isolation kit

Immunomagnetic positive selection cell isolation kit

Immunomagnetic negative selection kit

Immunomagnetic negative selection cell isolation kit

Activin A, animal component-free

Antioxidant; Reducing agent

Activin/Nodal/TGFß pathway inhibitor; Inhibits ALK2

BMP and AMPK pathway inhibitor; Inhibits ALK2, ALK3, ALK6, and AMPK

Antibiotic; Used in Tet-inducible gene expression systems

Retinoid pathway activator; Activates retinoic acid receptor (RAR)

Adenosine deaminase and PDE2 inhibitor

mTOR pathway inhibitor; Inhibits FKBP-12

Epigenetic modifier; Inhibits SIRT1 histone deacetylase

RHO/ROCK pathway inhibitor; Inhibits ROCK2

Calcineurin/NFAT pathway inhibitor; Binds FKBP-12

Serotonin reuptake inhibitor