Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
These racks maintain a temperature of less than 4°C for almost 3.5 hours (with the lid on the rack) at room temperature. Frosty Mate™ can be used for transportation of biological samples, chemicals etc. at a stable temperature for a long time. Consistently cooled samples – FROSTY MATETM color changes dramatically when the temperature of a rack containing samples reaches below 4°C. A clear visible color change from Gre…
Abdos PCR plates are manufactured in state of the art precision moulded facility using high purity virgin USP Class VI Medical grade polypropylene (PP) conforming to US FDA 21 CFR, free from natural rubber and heavy metal. Ultra thin and consistent wall thickness allows precise thermal transfer. Maximum G-Force 4000 RCF. Abdos PCR plates are qPCR compatible. DNase, RNase, Endotoxin and PCR inhibitor free.
Autoimmune disease autoantibody screening. Using the Pan-Autoimmune Protein Array 1.0, Sengenics can screen autoantibodies against more than 100 clinically relevant antigens in a wide range of autoimmune diseases. The Pan-Autoimmune Protein Array 1.0 service is ideal for focused autoimmune disease research.
The high speed Micronic Rack Reader DT520 is designed to quickly read single tubes and rack barcodes in one ergonomic device. Readout time is less than one second.
The BIOne benchtop scale single-use bioreactor (SUB) is for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds.
BIOne 1250 Controllers are compatible with both autoclavable and single-use vessels. The systems are also capable of supporting both cell culture and fermentation processes. Standard controller options such as OPC and Additional Input & Outputs expand the capabilities of the controller. Such features provide end-users with nearly limitless process expansion potential for whatever future bioprocesses they desire to engineer.…
Are you looking for additional labware positions and pipetting flexibility? The Avidien Dual Nest can be easily installed on a new or existing microPro to create a third labware position in a compact 96-channel semi-automated benchtop solution.
The world's smallest 96/384 channel semi-automated benchtop pipettor. This innovative compact instrument packs an enormous feature set that offers unprecedented capability and value. It is accurate, affordable, efficient, reliable and easy to use.
Pooled and Arrayed Genome-Wide LentiORF Libraries for High-Throughput Screens or Targeted Experiments
Recombinant PURedit Cas9 protein from Streptococcus pyogenes is a ready-to-use reagent for genome engineering experiments
Recombinant Cas9 Plus protein from Streptococcus pyogenes is a ready-to-use reagent for genome engineering experiments.
Recombinant Cas9-GFP protein from Streptococcus pyogenes is a ready-to-use reagent for genome engineering experiments.
Trusted TRC (The RNAi Consortium) content with shRNA targting 20,000+ human or 21,000+ mouse genes including TRC 1.5 and 2.0 (unique and validated) add-ons which are exclusive to Sigma
The human CRISPR ′Brunello′ pooled library is designed using optimized metrics, as published by, Doench et al. Nat Biotechnol. (2016) and described further in Sanson, K.R., et al. Nat Commun (2018)
The Human Whole Genome Toronto KnockOut Library v3 (TKOv3) is optimized for editing efficiency using empirical data described in the findings by the Moffat lab.
The human, paired guide Poison (pgPoison) library targets 3` splice sites with paired guide RNAs for alternative exon removal (pgRNAs), induce skipping of "poison" cassette exons and corresponding upstream constitutive exons in ultraconserved regions.
The mouse CRISPR "Brie" lentiviral pooled libraries are designed using optimized metrics, as published by Sanson, K.R., et al. Nat Commun 9, 5416 (2018), which combine improved on-target activity predictions (Rule Set 2) with an off-target score, the Cutting Frequency Determination (CFD)
The Human CRISPR inhibition (CRISPRi) library (Dolcetto) is a single compact library that inhibits over 18,000 human genes and is used for genome-wide inhibition screening using a KRAB-dCas9 effector.
MegaRobo, as the premier global provider of laboratory automation solutions, independently developed its sample reformatter and has received continuous praises from customers. The system integrates artificial intelligence and automated control for flexibility and for user-friendliness. The MRA-CDS-102 model can easily fit into biosafety cabinets with convenient installation.
Megarobo, as the premier provider of laboratory automation solutions in China. CDS-610 sample reformatter, as one of the highest throughput of a single device on the market, integrates steps requiring extensive manual operation into a closed negative pressure system, to achieve a fully automated sample preparation "tube in and plate out".
Megarobo's new MRA-LSF-840 series ultra-high-throughput kit assembly system can meet the needs of reagent card assembly in terms of throughput, compatibility, and yield. At the same time, it is equipped with card loading and packaging modules, and each module can be operated independently or combined for production.
Efficient: Up to 8000-10000 pcs/h Flexible: Compatible with multiple types of tubes such as disposable virus sampling tubes Intuitive: Visualization software & touch screen Modular: Including laminar flow, labeling and coding, and CCD modules, allows for personalization Stable: Stable operation, high yield rate Effortless: Only 1 -2 people are needed to complete the whole process
Efficient: Up to 8000-10000 pcs/h Flexible: Compatible with multiple types of tubes such as disposable virus sampling tubes Intuitive: Visualization software & touch screen Modular: Including laminar flow, labeling and coding, and CCD modules, allows for personalization Stable: Stable operation, high yield rate Effortless: Only 1 -2 people are needed to complete the whole process
The Organoid Analysis Module for the CytoSMART Omni systems is an advanced machine-learning algorithm for robust organoid quantification, tracking, and analysis.
The 10x Compatible Human CRISPRi Kinase Phosphatase Drug Targets Kit (Druggable Genome) contains one sub-pool of the top two ranked sgRNAs per gene for increased sensitivity and includes non-targeting controls built-in.
