Drug discovery > Target Discovery Products & Reviews

Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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CX & CXR Series

Taylor-Wharton

Cryo Express (CX) “dry shippers” are designed to safely transport a variety of materials at cryogenic temperatures. The unique absorbent material prevents a liquid spill if the unit is tipped over. Storage temperature inside the shipping cavity remains at approximately -190˚C until the liquid nitrogen evaporates from the absorbent material. CX & CXR Series Features: Advanced Concept Absorbent enables faster charging Co…

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XT Series

Taylor-Wharton

The Extended Time Series (XT) Series of cryogenic refrigerators are designed for long-term storage of a variety of materials at cryogenic temperatures. This series also offers low profile models (XTL), with 5” canisters. XT Series Features: New Rugged Construction – ribbed high strength aluminum body, magniformed necktube design, and more durable paint Versatile storage system – convenient canister numbered index location…

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Rocket 4D Synergy Large Volume Evaporator

Genevac

Rocket 4D Synergy is designed primarily to evaporate large sample volumes, with autofeed if required, allowing automatic evaporation of volumes up to 100 litres. Rocket 4D Synergy provides fast, safe evaporation for solvents with a boiling point of up to 165°C (DMF) and can easily dry aqueous samples. The system feeds the solution for evaporation to the evaporation vessel, controls temperature and pressure, prevents bumping…

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Magna ChIP™ HiSens Chromatin Immunoprecipitation Kit

Merck

The Magna ChIP HiSens kit provides a complete set of validated, quality controlled reagents, and a detailed protocol to enable ChIP from a wide range of input amounts of chromatin obtained from either cells or tissues. Our specialized blend of protein A/G blend of magnetic beads is specifically produced for chromatin immunoprecipiptation and enables the use of a broader range of antibodies than protein A or G alone eliminating…

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F2H Assay Kit

Chromotek GmbH

F2H®-Kit Basic for effortless imaging of interactions between GFP- and RFP-tagged proteins of interest and domains thereof in live mammalian cells. The Fluorescent Two- Hybrid (F2H®) Technology is a fast and simple way to study protein-protein interactions (PPIs) by conventional fluorescence microscopy. Its direct optical readout is optimal for high-content analysis (HCA) and screening for PPI inhibitors.F2H® Principle: F…

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MethylCap kit

Diagenode

The MethylCap assay is based on the affinity purification of methylated DNA using a MBD (Methylbinding domain) protein . This procedure has first been optimized on the SX-8G IP-Star Automated System ([page product SX-8G IP-Star]. Afterwards, this method has been adapted to a manual protocol, which has been inspired by the same reproducibility standards provided by the automated MethylCap assay. Allows for fractionati…

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PureEpi™ Chromatin Preparation and Optimization Kit

Merck

The PureEpi Chromatin Preparation and Optimization kit provides a complete set of reagents allowing the preparation of multiple chromatin samples from starting materials such as cultured cells or tissues. A detailed protocol is provided that includes examples of the many variables involved in making chromatin on multiple instruments and how they may affect ChIP results. Features & Benefits • Complete set of materials for up to…

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GeSiM Nano-Plotter™ Non-Contact Nanolitre Dispenser

Analytik Ltd

The Nano-Plotter™ series are ideal for generating high-quality spots by non-contact dispensing of sub-nanolitre volumes. The highly versatile “drop on demand” piezoelectric technology allows the placement of drops onto a variety of substrates with outstanding precision, and also the mixing of samples into pre-filled cavities to run nano-assays. These compact instruments are your ideal solution for the development and producti…

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DNAQual Kit

Eurobio Laboratories

DNAQual kit is used for the quantitative assessment of DNA degradation by quantifying the number of copies of a target gene compared to a calibrator gene (included in the kit) in any human DNA sample by qPCR in duplex in 90 minutes. The two genes (target and calibrator are measured with two specific probes carrying each a different fluorophore: Texas Red for the calibrator and VIC for the target gene. The software on the qPCR…

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Thermo-ShakeX ELM

Xiril AG

The Thermo-ShakeX ELM – working reliable, smooth and quet on a Xiril liquid handling robotic workstation – is the answer to all your automated plate shaking&heating needs. Thermo-ShakeX ELM Features: Edge locking mechanism (ELM) allows safe positioning and optimal gripping of different plate types Vibration- and splatter-free mixing in orbital motion, up to 3000 rpm All SBS format plate types easily shakeable* (*stan…

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