Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules. Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits: A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD)…
Mouse IL-6 R&D Quantikine ELISA Kit - Mouse IL-6 Immunoassay for the quantitative determination of mouse interleukin 6 (IL-6) concentrations in cell culture supernates, mouse serum, and plasma. The R&D Quantikine Mouse IL-6 ELSIA is a 4.5 hour solid-phase ELISA. This R&D Quantikine assay employs the quantitative sandwich enzyme immunoassay technique.R&D Systems Quantikine ELISA Kits are complete and ready-to-use. Features of…
R&D Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit - R&D Mouse IL-1/IL-1F2 Immunoassay for the quantitative determination of mouse interleukin 1 beta (IL-1ß) concentrations in cell culture supernates and mouse serum. The R&D Quantikine Mouse IL-1 Immunoassay is a 4.5 hour solid phase ELISA. This R&D Quantikine assay employs the quantitative sandwich enzyme immunoassay technique. Features of the R&D Quantikine ELISA Kit inclu…
The BD FACSAria™ Fusion improves on the solid foundation of patented technologies, exceptional multicolor performance, and ease-of-use that was first brought to the world of sorting by the launch of the BD FACSAria™ sorter in 2003. Now this sorting know-how is combined with best-in-class biosafety expertise to create the BD FACSAria Fusion, a fully integrated advanced cell sorter and biosafety solution for research laboratorie…
More than 18,000 studies have been published citing the use of the yeast two-hybrid system to investigate protein-protein interactions, and Clontech’s Matchmaker™ Systems have been by far the most popular. Matchmaker™ Gold Systems are the highest performing incarnations of our Matchmaker product line, due to a combination of a new yeast strain (Y2HGold), stringent reporters, easy to use libraries, high-level expression vectors…
The G-LISA™ assay uses a 96-well plate coated with RBD domain of Rho-family effector proteins. The active GTP-bound form of the Rho-family protein, but not the inactive GDP-bound form, from a biological sample will bind to the plate. Bound active Rho-family protein is then detected by incubation with a specific primary antibody followed by a secondary antibody conjugated to HRP. The signal is then developed with OPD or chemilu…
The NL100 Nitrogen Laser is ideal for fluorescence measurements, MALDI-TOF mass spectrometers, and other pulsed UV radiation experiments. It provides 3.5 ns pulses at 337 nm (UV), with repetition rates up to 20 Hz. The pulse energy is 170 µJ, which results in a peak power of 45 kW and an average power of 3 mW. The NL100 can be triggered internally or externally at rates up to 20 Hz. It can also provide a sync output pulse (opt…
The SNAP i.d. Protein Detection System revolutionizes the quality of your blots every time — in record time! Unlike conventional Western blotting, where diffusion is the primary means of reagent transport, the SNAP i.d. system applies a vacuum to actively drive reagents through the membrane. This novel method allows you to optimize your blotting conditions in record time for maximum results. The SNAP i.d. system minimizes over…
Each VECTASTAIN® ABC kit utilizes the same preformed Avidin: Biotinylated enzyme Complex (ABC) principle and all offer low backgrounds and an amplification of signal compared to conven-tional covalent conjugates. The high sensitivity reported for this technique likely resides in either the form or the number of active enzyme molecules associated with the complex and the rapid, irreversible interaction of the complex with bio…
Sample preparation for a wide range of analysis types, sample dissolution, serial dilutions, reformatting steps and much more can be fully automated with Zinsser’s flexible liquid handling system, LISSY. LISSY is available in various standard configurations: from 90cm up to 200cm in length, from 1 up to 16 pipetting probes, with or without integrated gripper for moving plates, individual tubes or tools, etc. As with all Zinsse…
Fill-It - is an automated benchtop system for filling screw-cap cryovials. Fill-It is designed to help create cell banks of higher quality, consistency and viability. It combines proven decap / recap modules with aseptic liquid handling. Fill-It removes all screw caps simultaneously and then dispenses into multiple cryovials in parallel. Compatible with Corning, Greiner, Micronic, Matrix, Nalgene, Nunc and Sarstedt screw-cap c…
The Thermo Scientific TSQ Quantum Ultra mass spectrometer provides ultimate productivity for bioanalytical analysis. Faster method development at the highest possible specificity is routinely achievable with the TSQ Quantum Ultra™ mass spectrometer. Featuring the patented Thermo Scientific HyperQuad quadrupole mass analyzer system, the TSQ Quantum Ultra performs highly selective reaction monitoring (H-SRM), which provides gr…
Your benchmark for fluorescent protein flow cytometry
High Resolution Melting (HRM) analysis is a post-PCR analysis method used to identify genetic variation in nucleic acid sequences. The MeltDoctor™ HRM Master Mix contains all components (excluding template and primers) formulated for superior HRM performance across a wide range of genomic targets. Unlike some competitive mixes, the MeltDoctor™ HRM Master Mix does not require additional mixing prior to use, and was developed…
The MagNA Pure 96 System from Roche Applied Science has been designed and engineered to meet the needs for high throughput laboratories worldwide. The integrated system enables batch processing of up to 96 samples in parallel ensuring every sample is treated exactly the same while providing extremely quick turnaround time. These characteristics result in a low sample processing time; for typical standard applications, 96 sampl…
Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…
Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…
The Echo® liquid handler revolutionizes liquid handling with acoustic energy. Sound waves eject precisely sized droplets from a source onto a microplate, slide or other surface suspended above the source. This product does not use tips, pin tools or nozzles—completely eliminating contact between the instrument and the liquid. The Echo liquid handler provides powerful benefits: Tipless transfer, resulting in dramatic cost s…
HyClone Fetal Bovine Serum - Thermo HyClone Fetal Bovine Serum, U.S. Origin is filtered through serial 40µm (0.04µm) pore-size rated filters. Eliminate concerns about viral contamination in Fetal Bovine Serum (FBS) without compromising cell culture performance. HyClone FBS is widely used by those culturists who require an extensive biochemical profile. Defined FBS is filtered through the most retentive filters used in commerci…
Roche NimbleGen provides a unique combination of high-density arrays, long-oligo probes, and flexible design capability that together provide superior results for advanced gene expression analysis. NimbleGen microarrays enable accurate, sensitive, and specific interrogation of genome-wide expression for any sequenced and annotated genome. Researchers also can tile through a genome at any desired spacing to discover genome-wide…
Chemical Name: (RS)-3,5-Dihydroxyphenylglycine Selective group I metabotropic glutamate receptor agonist which activates both mGlu1 and mGlu5. Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D. Selective group I mGlu agonist.
The Luminex® 200™ detects up to 100 protein or nucleic acid analytes from a single aliquot of sample in a single reaction well, enabling you to generate more data while saving sample, time, and reagents. With more than 11,000 units sold globally to date, the Luminex 100/200 is the established standard in multiplexing instrumentation. The xMAP® multiplexing platform is composed of an instrument and associated reagents: Th…
SAXSpace is a new nanostructure analyzer for small- and wide-angle X-ray scattering (SWAXS) studies of nanostructured materials. With its easy handling and push-button alignment, SAXSpace is ideally suited for routine SWAXS analysis and quality control applications. SAXS experts benefit from the spacious sample chamber and versatile sample stages, allowing for full experimental flexibility. This makes SAXSpace an ideal tool fo…
Premiere liquid handling workstation: reliability in a new compact package. With over 40 years of experience in automated liquid handling, the Tomtec Quadra4TM is the latest incarnation of a best in class rugged, cost effective liquid handling workstation for life science work-flows. Whether you are doing in-vitro research, developing new molecular entities, conducting solid-phase extraction or serial-dilution - the Quadra4TM…
The Thermo Scientific & The Automation Partnership (TAP) Capit-All removes and replaces screw caps on 96-format storage tubes with precision and ease. The instrument's robust design ensures reliable, high throughput access and storage of samples in Thermo Scientific Matrix®, Nunc® and other screw cap storage tubes, while reducing risk of repetitive strain injury.Benefits • Increase laboratory throughput • Enhance ergonomics •…
